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F12 coagulation factor XII [ Sturnira hondurensis ]

Gene ID: 118999765, updated on 30-Mar-2024

Summary

Gene symbol
F12
Gene description
coagulation factor XII
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnira hondurensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Stenodermatinae; Sturnira
Orthologs
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Genomic context

See F12 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100.20210611 current WHU_Shon_v2.1 (GCF_014824575.2) Unplaced Scaffold NW_023522157.1 (1655592..1663057, complement)

NW_023522157.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 34 member 1 Neighboring gene profilin 3 Neighboring gene G protein-coupled receptor kinase 6 Neighboring gene proline rich 7, synaptic

Genomic regions, transcripts, and products

Genomic Sequence:
NW_023522157 Unplaced Scaffold Reference WHU_Shon_v2.1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in rough endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnira hondurensis Updated Annotation Release 100.20210611

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference WHU_Shon_v2.1

Genomic

  1. NW_023522157.1 Reference WHU_Shon_v2.1

    Range
    1655592..1663057 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037064509.1XP_036920404.1  coagulation factor XII

    Conserved Domains (6) summary
    cd00054
    Location:170205
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00061
    Location:207247
    FN1; Fibronectin type 1 domain, approximately 40 residue long with two conserved disulfide bridges. FN1 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces ...
    cd00062
    Location:115162
    FN2; Fibronectin Type II domain: FN2 is one of three types of internal repeats which combine to form larger domains within fibronectin. Fibronectin, a plasma protein that binds cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and ...
    cd00190
    Location:434675
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00008
    Location:252281
    EGF; EGF-like domain
    pfam00051
    Location:291369
    Kringle; Kringle domain