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AGRN agrin [ Sturnira hondurensis ]

Gene ID: 118998230, updated on 30-Mar-2024

Summary

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Gene symbol
AGRN
Gene description
agrin
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnira hondurensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Stenodermatinae; Sturnira
Orthologs
human mouse all
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Genomic context

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See AGRN in Genome Data Viewer
Location:
chromosome: Un
Exon count:
39
Annotation release Status Assembly Chr Location
100.20210611 current WHU_Shon_v2.1 (GCF_014824575.2) Unplaced Scaffold NW_023520724.1 (4685021..4716543, complement)

NW_023520724.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C1orf159 homolog Neighboring gene ring finger protein 223 Neighboring gene ISG15 ubiquitin like modifier Neighboring gene hes family bHLH transcription factor 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023520724 Unplaced Scaffold Reference WHU_Shon_v2.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor clustering IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
agrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnira hondurensis Updated Annotation Release 100.20210611

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference WHU_Shon_v2.1

Genomic

  1. NW_023520724.1 Reference WHU_Shon_v2.1

    Range
    4685021..4716543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037062267.1 → XP_036918162.1  agrin isoform X3

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1134 → 1258
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1810 → 1842
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1365 → 1515
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1322 → 1352
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1657 → 1788
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:978 → 1098
    gliding_GltJ; adventurous gliding motility protein GltJ

  2. XM_037062265.1 → XP_036918160.1  agrin isoform X1

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1134 → 1258
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1814 → 1846
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1365 → 1515
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1322 → 1352
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1657 → 1792
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:978 → 1098
    gliding_GltJ; adventurous gliding motility protein GltJ

  3. XM_037062268.1 → XP_036918163.1  agrin isoform X4

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1128 → 1252
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1808 → 1840
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1359 → 1509
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1316 → 1346
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1651 → 1786
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:970 → 1092
    gliding_GltJ; adventurous gliding motility protein GltJ

  4. XM_037062266.1 → XP_036918161.1  agrin isoform X2

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1134 → 1258
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1810 → 1842
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1365 → 1515
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1322 → 1352
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1657 → 1788
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:978 → 1098
    gliding_GltJ; adventurous gliding motility protein GltJ

  5. XM_037062269.1 → XP_036918164.1  agrin isoform X5

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1134 → 1258
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1814 → 1846
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1365 → 1515
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1322 → 1352
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1657 → 1792
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:978 → 1098
    gliding_GltJ; adventurous gliding motility protein GltJ

  6. XM_037062270.1 → XP_036918165.1  agrin isoform X6

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1134 → 1258
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1810 → 1842
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1365 → 1515
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1322 → 1352
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1657 → 1788
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:978 → 1098
    gliding_GltJ; adventurous gliding motility protein GltJ

  7. XM_037062273.1 → XP_036918168.1  agrin isoform X9

    Conserved Domains (10) summary
    smart00280
    Location:491 → 536
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1128 → 1252
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1804 → 1836
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:423 → 463
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1359 → 1509
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1316 → 1346
    EGF; EGF-like domain
    pfam00053
    Location:795 → 837
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1651 → 1782
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:46 → 148
    NtA; Agrin NtA domain
    NF033761
    Location:970 → 1092
    gliding_GltJ; adventurous gliding motility protein GltJ

  8. XM_037062272.1 → XP_036918167.1  agrin isoform X8

    Conserved Domains (9) summary
    smart00280
    Location:384 → 429
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1021 → 1145
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1701 → 1733
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:316 → 356
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1252 → 1402
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1209 → 1239
    EGF; EGF-like domain
    pfam00053
    Location:688 → 730
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1544 → 1679
    Laminin_G_1; Laminin G domain
    NF033761
    Location:863 → 990
    gliding_GltJ; adventurous gliding motility protein GltJ

  9. XM_037062271.1 → XP_036918166.1  agrin isoform X7

    Conserved Domains (9) summary
    smart00280
    Location:384 → 429
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1027 → 1151
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1707 → 1739
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:316 → 356
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1258 → 1408
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1215 → 1245
    EGF; EGF-like domain
    pfam00053
    Location:688 → 730
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1550 → 1685
    Laminin_G_1; Laminin G domain
    NF033761
    Location:871 → 996
    gliding_GltJ; adventurous gliding motility protein GltJ

  10. XM_037062274.1 → XP_036918169.1  agrin isoform X10

    Conserved Domains (9) summary
    smart00280
    Location:384 → 429
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1021 → 1145
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1701 → 1733
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:316 → 356
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    cd00110
    Location:1252 → 1402
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:1209 → 1239
    EGF; EGF-like domain
    pfam00053
    Location:688 → 730
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1544 → 1679
    Laminin_G_1; Laminin G domain
    NF033761
    Location:863 → 990
    gliding_GltJ; adventurous gliding motility protein GltJ
Nucleotide Protein
Heading Accession and Version

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