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TJP2 tight junction protein 2 [ Sturnira hondurensis ]

Gene ID: 118997833, updated on 30-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnira hondurensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Stenodermatinae; Sturnira
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
100.20210611 current WHU_Shon_v2.1 (GCF_014824575.2) Unplaced Scaffold NW_023520286.1 (3111990..3227421, complement)

NW_023520286.1Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene 40S ribosomal protein S12-like Neighboring gene frataxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023520286 Unplaced Scaffold Reference WHU_Shon_v2.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnira hondurensis Updated Annotation Release 100.20210611

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference WHU_Shon_v2.1

Genomic

  1. NW_023520286.1 Reference WHU_Shon_v2.1

    Range
    3111990..3227421 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037061702.1 → XP_036917597.1  tight junction protein ZO-2 isoform X6

    Conserved Domains (5) summary
    cd12027
    Location:593 → 655
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:689 → 868
    GuKc; Guanylate kinase homologues
    smart00228
    Location:293 → 374
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:132 → 229
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  2. XM_037061699.1 → XP_036917594.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (5) summary
    cd12027
    Location:675 → 737
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:771 → 950
    GuKc; Guanylate kinase homologues
    smart00228
    Location:375 → 456
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:214 → 311
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  3. XM_037061697.1 → XP_036917592.1  tight junction protein ZO-2 isoform X1

    Conserved Domains (5) summary
    cd12027
    Location:675 → 737
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:771 → 950
    GuKc; Guanylate kinase homologues
    smart00228
    Location:375 → 456
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:91 → 176
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:214 → 311
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  4. XM_037061700.1 → XP_036917595.1  tight junction protein ZO-2 isoform X4

    Conserved Domains (5) summary
    cd12027
    Location:616 → 678
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:712 → 891
    GuKc; Guanylate kinase homologues
    smart00228
    Location:316 → 397
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:155 → 252
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  5. XM_037061701.1 → XP_036917596.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (5) summary
    cd12027
    Location:620 → 682
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:716 → 895
    GuKc; Guanylate kinase homologues
    smart00228
    Location:320 → 401
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:159 → 256
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  6. XM_037061698.1 → XP_036917593.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (5) summary
    cd12027
    Location:620 → 682
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:716 → 895
    GuKc; Guanylate kinase homologues
    smart00228
    Location:320 → 401
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:159 → 256
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
Nucleotide Protein
Heading Accession and Version

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