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MASP2 MBL associated serine protease 2 [ Sturnira hondurensis ]

Gene ID: 118986356, updated on 30-Mar-2024

Summary

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Gene symbol
MASP2
Gene description
MBL associated serine protease 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnira hondurensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Stenodermatinae; Sturnira
Orthologs
human mouse all
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Genomic context

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See MASP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100.20210611 current WHU_Shon_v2.1 (GCF_014824575.2) Unplaced Scaffold NW_023510470.1 (5044748..5059700)

NW_023510470.1Genomic Context describing neighboring genes Neighboring gene exosome component 10 Neighboring gene spermidine synthase Neighboring gene TAR DNA binding protein Neighboring gene uncharacterized LOC118986358

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023510470 Unplaced Scaffold Reference WHU_Shon_v2.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation, lectin pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnira hondurensis Updated Annotation Release 100.20210611

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference WHU_Shon_v2.1

Genomic

  1. NW_023510470.1 Reference WHU_Shon_v2.1

    Range
    5044748..5059700
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037045242.1 → XP_036901137.1  mannan-binding lectin serine protease 2 isoform X1

    Conserved Domains (5) summary
    smart00042
    Location:28 → 134
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    smart00179
    Location:138 → 180
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:445 → 683
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:300 → 361
    Sushi; Sushi repeat (SCR repeat)

  2. XM_037045245.1 → XP_036901140.1  mannan-binding lectin serine protease 2 isoform X3

    Conserved Domains (4) summary
    cd00033
    Location:300 → 339
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00042
    Location:28 → 134
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    smart00179
    Location:138 → 180
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  3. XM_037045243.1 → XP_036901138.1  mannan-binding lectin serine protease 2 isoform X2

    Conserved Domains (4) summary
    smart00042
    Location:28 → 134
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    smart00179
    Location:138 → 180
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:300 → 361
    Sushi; Sushi repeat (SCR repeat)

  4. XM_037045246.1 → XP_036901141.1  mannan-binding lectin serine protease 2 isoform X4

    Conserved Domains (2) summary
    smart00042
    Location:28 → 134
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    smart00179
    Location:138 → 180
    EGF_CA; Calcium-binding EGF-like domain
Nucleotide Protein
Heading Accession and Version

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