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TJP2 tight junction protein 2 [ Balaenoptera musculus (blue whale) ]

Gene ID: 118897167, updated on 20-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
EnsemblRapid:ENSBMSG00010000778
Gene type
protein coding
RefSeq status
MODEL
Organism
Balaenoptera musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
29
Annotation release Status Assembly Chr Location
100 current mBalMus1.pri.v3 (GCF_009873245.2) 6 NC_045790.1 (66065946..66198598)

Chromosome 6 - NC_045790.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene uncharacterized LOC118897173 Neighboring gene uncharacterized LOC118897172 Neighboring gene frataxin Neighboring gene UDP-N-acetylglucosamine transporter-like Neighboring gene hypoxanthine-guanine phosphoribosyltransferase-like Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene amyloid beta precursor protein binding family A member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045790.1 Chromosome 6 Reference mBalMus1.pri.v3 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Balaenoptera musculus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mBalMus1.pri.v3 Primary Assembly

Genomic

  1. NC_045790.1 Reference mBalMus1.pri.v3 Primary Assembly

    Range
    66065946..66198598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036856080.1 → XP_036711975.1  tight junction protein ZO-2 isoform X6

    UniProtKB/TrEMBL
    A0A8B8XXC3, A0A8C0HSV2
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:272 → 353
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 262
    RSRP; Arginine/Serine-Rich protein 1

  2. XM_036856082.1 → XP_036711977.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0C5U2, A0A8C0HSV2
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:272 → 353
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 284
    RSRP; Arginine/Serine-Rich protein 1

  3. XM_036856081.1 → XP_036711976.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0C5U2, A0A8C0HSV2
    Related
    ENSBMSP00010001183.1, ENSBMST00010001310.2
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:272 → 353
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 284
    RSRP; Arginine/Serine-Rich protein 1

  4. XM_036856077.1 → XP_036711972.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0C5U2, A0A8C0HSV2
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:272 → 353
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 284
    RSRP; Arginine/Serine-Rich protein 1

  5. XM_036856075.1 → XP_036711970.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0C5U2, A0A8C0HSV2
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:272 → 353
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 284
    RSRP; Arginine/Serine-Rich protein 1

  6. XM_036856074.1 → XP_036711969.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C0C8R8, A0A8C0HSV2
    Related
    ENSBMSP00010001235.1, ENSBMST00010001368.2
    Conserved Domains (5) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 376
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:148 → 307
    RSRP; Arginine/Serine-Rich protein 1

  7. XM_036856079.1 → XP_036711974.1  tight junction protein ZO-2 isoform X5

    UniProtKB/TrEMBL
    A0A8B8XQW6, A0A8C0HSV2
    Related
    ENSBMSP00010032782.1, ENSBMST00010036754.1
    Conserved Domains (5) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 376
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:148 → 285
    RSRP; Arginine/Serine-Rich protein 1

  8. XM_036856076.1 → XP_036711971.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C0C5U2, A0A8C0HSV2
    Conserved Domains (5) summary
    cd12027
    Location:572 → 634
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:668 → 847
    GuKc; Guanylate kinase homologues
    smart00228
    Location:272 → 353
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 284
    RSRP; Arginine/Serine-Rich protein 1

  9. XM_036856072.1 → XP_036711967.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8B8XQ36, A0A8C0HSV2
    Conserved Domains (5) summary
    cd12027
    Location:599 → 661
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:695 → 874
    GuKc; Guanylate kinase homologues
    smart00228
    Location:299 → 380
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:152 → 311
    RSRP; Arginine/Serine-Rich protein 1

  10. XM_036856078.1 → XP_036711973.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A8B8XQ53, A0A8C0HSV2
    Related
    ENSBMSP00010001269.1, ENSBMST00010001404.2
    Conserved Domains (5) summary
    cd12027
    Location:599 → 661
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:695 → 874
    GuKc; Guanylate kinase homologues
    smart00228
    Location:299 → 380
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:152 → 289
    RSRP; Arginine/Serine-Rich protein 1
Nucleotide Protein
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