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TJP2 tight junction protein 2 [ Pipistrellus kuhlii (Kuhl's pipistrelle) ]

Gene ID: 118716511, updated on 30-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
Locus tag
mPipKuh1_017443
Gene type
protein coding
RefSeq status
MODEL
Organism
Pipistrellus kuhlii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Pipistrellus
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
101 current mPipKuh1.p (GCF_014108245.1) Unplaced Scaffold NW_023425427.1 (30816024..30923115, complement)

NW_023425427.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123652141 Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene uncharacterized LOC123652142 Neighboring gene frataxin Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023425427 Unplaced Scaffold Reference mPipKuh1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pipistrellus kuhlii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPipKuh1.p

Genomic

  1. NW_023425427.1 Reference mPipKuh1.p

    Range
    30816024..30923115 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036433870.2 → XP_036289763.1  tight junction protein ZO-2 isoform X10

    UniProtKB/TrEMBL
    A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:582 → 644
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:678 → 857
    GuKc; Guanylate kinase homologues
    smart00228
    Location:290 → 367
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:156 → 276
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  2. XM_036433861.1 → XP_036289754.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A7J7W4P5
    Conserved Domains (5) summary
    cd12027
    Location:668 → 730
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:764 → 943
    GuKc; Guanylate kinase homologues
    smart00228
    Location:376 → 453
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:99 → 180
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:217 → 333
    SF-CC1; splicing factor, CC1-like family

  3. XM_036433862.1 → XP_036289755.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    A0A7J7W413
    Conserved Domains (5) summary
    cd12027
    Location:582 → 644
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:678 → 857
    GuKc; Guanylate kinase homologues
    smart00228
    Location:290 → 367
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:131 → 247
    SF-CC1; splicing factor, CC1-like family

  4. XM_036433866.2 → XP_036289759.1  tight junction protein ZO-2 isoform X6

    UniProtKB/TrEMBL
    A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:587 → 649
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:683 → 862
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 372
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:21 → 99
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:161 → 281
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  5. XM_036433865.2 → XP_036289758.1  tight junction protein ZO-2 isoform X5

    UniProtKB/TrEMBL
    A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:605 → 667
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:701 → 880
    GuKc; Guanylate kinase homologues
    smart00228
    Location:313 → 390
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:179 → 299
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  6. XM_036433864.1 → XP_036289757.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:609 → 671
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:705 → 884
    GuKc; Guanylate kinase homologues
    smart00228
    Location:317 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:183 → 303
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  7. XM_036433869.2 → XP_036289762.1  tight junction protein ZO-2 isoform X9

    UniProtKB/TrEMBL
    A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:519 → 581
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:615 → 794
    GuKc; Guanylate kinase homologues
    smart00228
    Location:227 → 304
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:425 → 502
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:93 → 213
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  8. XM_036433867.2 → XP_036289760.1  tight junction protein ZO-2 isoform X7

    UniProtKB/TrEMBL
    A0A7J7W413, A0A7J7W432
    Conserved Domains (5) summary
    cd12027
    Location:582 → 644
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:678 → 857
    GuKc; Guanylate kinase homologues
    smart00228
    Location:290 → 367
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:156 → 276
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  9. XM_036433863.2 → XP_036289756.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A7J7W4M7, A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:582 → 644
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:678 → 857
    GuKc; Guanylate kinase homologues
    smart00228
    Location:290 → 367
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:156 → 276
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  10. XM_036433871.2 → XP_036289764.1  tight junction protein ZO-2 isoform X11

    UniProtKB/TrEMBL
    A0A7J7W413, A0A7J7W446
    Conserved Domains (5) summary
    cd12027
    Location:609 → 671
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:705 → 884
    GuKc; Guanylate kinase homologues
    smart00228
    Location:317 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:183 → 303
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  11. XM_036433868.2 → XP_036289761.1  tight junction protein ZO-2 isoform X8

    UniProtKB/TrEMBL
    A0A7J7W4T4
    Conserved Domains (5) summary
    cd12027
    Location:609 → 671
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:705 → 884
    GuKc; Guanylate kinase homologues
    smart00228
    Location:317 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:183 → 303
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
Nucleotide Protein
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