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TDP2 tyrosyl-DNA phosphodiesterase 2 [ Myotis myotis ]

Gene ID: 118673659, updated on 30-Mar-2024

Summary

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Gene symbol
TDP2
Gene description
tyrosyl-DNA phosphodiesterase 2
Locus tag
mMyoMyo1_018908
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis myotis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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See TDP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416322.1 (42608133..42616231, complement)

NW_023416322.1Genomic Context describing neighboring genes Neighboring gene glycosylphosphatidylinositol specific phospholipase D1 Neighboring gene aldehyde dehydrogenase 5 family member A1 Neighboring gene acyl-CoA thioesterase 13 Neighboring gene chromosome unknown C6orf62 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023416322 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosyl-DNA phosphodiesterase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMyoMyo1.p Primary Assembly

Genomic

  1. NW_023416322.1 Reference mMyoMyo1.p Primary Assembly

    Range
    42608133..42616231 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036344760.1 → XP_036200653.1  tyrosyl-DNA phosphodiesterase 2 isoform X3

    UniProtKB/TrEMBL
    A0A7J7SUT5
    Conserved Domains (2) summary
    cd09080
    Location:157 → 352
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:70 → 106
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  2. XM_036344758.1 → XP_036200651.1  tyrosyl-DNA phosphodiesterase 2 isoform X1

    UniProtKB/TrEMBL
    A0A7J7SUT5
    Conserved Domains (2) summary
    cd09080
    Location:157 → 409
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:70 → 106
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  3. XM_036344759.1 → XP_036200652.1  tyrosyl-DNA phosphodiesterase 2 isoform X2

    UniProtKB/TrEMBL
    A0A7J7SUT5
    Conserved Domains (2) summary
    cd09080
    Location:157 → 401
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:70 → 106
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  4. XM_036344761.1 → XP_036200654.1  tyrosyl-DNA phosphodiesterase 2 isoform X4

    Conserved Domains (2) summary
    cd09080
    Location:157 → 323
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:70 → 106
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  5. XM_036344763.1 → XP_036200656.1  tyrosyl-DNA phosphodiesterase 2 isoform X5

    Conserved Domains (2) summary
    cd09080
    Location:157 → 318
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:70 → 106
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
Nucleotide Protein
Heading Accession and Version

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