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CAPN3 calpain 3 [ Myotis myotis ]

Gene ID: 118650353, updated on 30-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Locus tag
mMyoMyo1_002060
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis myotis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current mMyoMyo1.p (GCF_014108235.1) Unplaced Scaffold NW_023416313.1 (160723295..160774351)

NW_023416313.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene U6 spliceosomal RNA Neighboring gene elongation factor 1-alpha 1-like Neighboring gene glucosidase alpha, neutral C Neighboring gene zinc finger protein 106 Neighboring gene synaptosome associated protein 23

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023416313 Unplaced Scaffold Reference mMyoMyo1.p Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis myotis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMyoMyo1.p Primary Assembly

Genomic

  1. NW_023416313.1 Reference mMyoMyo1.p Primary Assembly

    Range
    160723295..160774351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036298750.1 → XP_036154643.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A7J8AIJ0
    Conserved Domains (4) summary
    cd16190
    Location:648 → 816
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:75 → 410
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:431 → 569
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:578 → 648
    Calpain_u2; Unstructured region on Calpain-3

  2. XM_036298759.1 → XP_036154652.1  calpain-3 isoform X2

    Conserved Domains (3) summary
    cd16190
    Location:610 → 778
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:75 → 410
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:431 → 569
    Calpain_III; Calpain large subunit, domain III

  3. XM_036298768.1 → XP_036154661.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A7J8AHW0
    Conserved Domains (3) summary
    cd16190
    Location:604 → 772
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:75 → 410
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:431 → 569
    Calpain_III; Calpain large subunit, domain III

  4. XM_036298775.1 → XP_036154668.1  calpain-3 isoform X4

    Conserved Domains (3) summary
    cd16190
    Location:561 → 729
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:75 → 367
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:388 → 526
    Calpain_III; Calpain large subunit, domain III
Nucleotide Protein
Heading Accession and Version

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