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LOC118390018 E3 ubiquitin-protein ligase CBL-like [ Oncorhynchus keta (chum salmon) ]

Gene ID: 118390018, updated on 23-Nov-2023

Summary

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Gene symbol
LOC118390018
Gene description
E3 ubiquitin-protein ligase CBL-like
See related
EnsemblRapid:ENSOKEG00005002944
Gene type
protein coding
RefSeq status
MODEL
Organism
Oncorhynchus keta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
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Genomic context

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See LOC118390018 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_03 current Oket_V2 (GCF_023373465.1) 11 NC_068431.1 (28732364..28762549, complement)

Chromosome 11 - NC_068431.1Genomic Context describing neighboring genes Neighboring gene protein MIS12 homolog Neighboring gene cell surface glycoprotein MUC18-like Neighboring gene uncharacterized LOC127933113 Neighboring gene alkB homolog 4, lysine demthylase Neighboring gene leucine-rich repeats and WD repeat domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_068431.1 Chromosome 11 Reference Oket_V2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023373465.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Oket_V2 Primary Assembly

Genomic

  1. NC_068431.1 Reference Oket_V2 Primary Assembly

    Range
    28732364..28762549 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035780131.2 → XP_035636024.1  E3 ubiquitin-protein ligase CBL-like isoform X1

    Conserved Domains (5) summary
    cd09920
    Location:247 → 343
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14393
    Location:820 → 859
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:353 → 418
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:45 → 163
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:170 → 253
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  2. XM_035780130.2 → XP_035636023.1  E3 ubiquitin-protein ligase CBL-like isoform X1

    Related
    ENSOKEP00005005367.1, ENSOKET00005006016.1
    Conserved Domains (5) summary
    cd09920
    Location:247 → 343
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14393
    Location:820 → 859
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:353 → 418
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:45 → 163
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:170 → 253
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  3. XM_052529846.1 → XP_052385806.1  E3 ubiquitin-protein ligase CBL-like isoform X1

  4. XM_035780133.2 → XP_035636026.1  E3 ubiquitin-protein ligase CBL-like isoform X2

    Related
    ENSOKEP00005005360.1, ENSOKET00005006009.1
    Conserved Domains (5) summary
    cd09920
    Location:239 → 335
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14393
    Location:812 → 851
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:345 → 410
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:37 → 155
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:162 → 245
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  5. XM_035780134.2 → XP_035636027.1  E3 ubiquitin-protein ligase CBL-like isoform X2

    Conserved Domains (5) summary
    cd09920
    Location:239 → 335
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14393
    Location:812 → 851
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:345 → 410
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:37 → 155
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:162 → 245
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein Strain
Heading Accession and Version

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