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tjp2a tight junction protein 2a (zona occludens 2) [ Scophthalmus maximus (turbot) ]

Gene ID: 118285161, updated on 10-Oct-2024

Summary

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Gene symbol
tjp2a
Gene description
tight junction protein 2a (zona occludens 2)
See related
EnsemblRapid:ENSSMAG00025012019
Gene type
protein coding
RefSeq status
MODEL
Organism
Scophthalmus maximus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Scophthalmidae; Scophthalmus
Also known as
ZO-2
Orthologs
zebrafish all
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Genomic context

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See tjp2a in Genome Data Viewer
Location:
chromosome: 20
Exon count:
27
Annotation release Status Assembly Chr Location
101 current ASM2237912v1 (GCF_022379125.1) 20 NC_061534.1 (2416403..2442661)
100 previous assembly ASM1334776v1 (GCF_013347765.1) 16 NC_049703.1 (2414983..2441218)

Chromosome 20 - NC_061534.1Genomic Context describing neighboring genes Neighboring gene oocyte zinc finger protein XlCOF6-like Neighboring gene uncharacterized LOC118285168 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase, type I, beta a Neighboring gene amyloid-beta A4 precursor protein-binding family A member 1-like Neighboring gene MAM domain-containing protein 2 Neighboring gene solute carrier family 30 member 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. High-throughput sequence analysis of turbot (Scophthalmus maximus) transcriptome using 454-pyrosequencing for the discovery of antiviral immune genes. Pereiro P, et al. PLoS One, 2012. PMID 22629298, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Scophthalmus maximus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2237912v1 Primary Assembly

Genomic

  1. NC_061534.1 Reference ASM2237912v1 Primary Assembly

    Range
    2416403..2442661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035608603.2 → XP_035464496.1  tight junction protein ZO-2a isoform X5

    UniProtKB/TrEMBL
    A0A8D3AS88
    Related
    ENSSMAP00025039782.1, ENSSMAT00025041401.1
    Conserved Domains (4) summary
    smart00072
    Location:734 → 912
    GuKc; Guanylate kinase homologues
    cd00992
    Location:14 → 99
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:167 → 295
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:634 → 699
    SH3; Src Homology 3 domain superfamily

  2. XM_035608604.2 → XP_035464497.1  tight junction protein ZO-2a isoform X6

    UniProtKB/TrEMBL
    A0A8D3AS88
    Conserved Domains (4) summary
    smart00072
    Location:729 → 907
    GuKc; Guanylate kinase homologues
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:162 → 290
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:629 → 694
    SH3; Src Homology 3 domain superfamily

  3. XM_035608606.2 → XP_035464499.1  tight junction protein ZO-2a isoform X8

    UniProtKB/TrEMBL
    A0A8D3AS88
    Related
    ENSSMAP00025039779.1, ENSSMAT00025041398.1
    Conserved Domains (4) summary
    smart00072
    Location:733 → 911
    GuKc; Guanylate kinase homologues
    cd00992
    Location:14 → 99
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:167 → 295
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:633 → 698
    SH3; Src Homology 3 domain superfamily

  4. XM_035608602.2 → XP_035464495.1  tight junction protein ZO-2a isoform X4

    UniProtKB/TrEMBL
    A0A8D3AS71
    Related
    ENSSMAP00025039776.1, ENSSMAT00025041395.1
    Conserved Domains (4) summary
    smart00072
    Location:752 → 930
    GuKc; Guanylate kinase homologues
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:185 → 313
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:652 → 717
    SH3; Src Homology 3 domain superfamily

  5. XM_047329663.1 → XP_047185619.1  tight junction protein ZO-2a isoform X7

    Related
    ENSSMAP00025039775.1, ENSSMAT00025041394.1

  6. XM_035608599.2 → XP_035464492.1  tight junction protein ZO-2a isoform X1

    UniProtKB/TrEMBL
    A0A8D3AS88
    Conserved Domains (4) summary
    smart00072
    Location:756 → 934
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:189 → 317
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:656 → 721
    SH3; Src Homology 3 domain superfamily

  7. XM_035608601.2 → XP_035464494.1  tight junction protein ZO-2a isoform X3

    UniProtKB/TrEMBL
    A0A8D3C8U0
    Conserved Domains (4) summary
    smart00072
    Location:756 → 934
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:189 → 317
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:656 → 721
    SH3; Src Homology 3 domain superfamily

  8. XM_035608600.2 → XP_035464493.1  tight junction protein ZO-2a isoform X2

    UniProtKB/TrEMBL
    A0A8D3AS88
    Related
    ENSSMAP00025039771.1, ENSSMAT00025041390.1
    Conserved Domains (4) summary
    smart00072
    Location:755 → 933
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:189 → 317
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:655 → 720
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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