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TRAF2 TNF receptor associated factor 2 [ Cygnus atratus (black swan) ]

Gene ID: 118260735, updated on 20-Mar-2024

Summary

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Gene symbol
TRAF2
Gene description
TNF receptor associated factor 2
See related
EnsemblRapid:ENSACYG00000013395
Gene type
protein coding
RefSeq status
MODEL
Organism
Cygnus atratus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anserinae; Cygnus
Orthologs
human mouse all
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Genomic context

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See TRAF2 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_02 current CAtr_DNAZoo_HiC_assembly (GCF_013377495.2) 19 NC_066380.1 (11698257..11724346)
100 previous assembly Cygnus_atratus_primary_v1.0 (GCF_013377495.1) Unplaced Scaffold NW_023336775.1 (400175..426286, complement)

Chromosome 19 - NC_066380.1Genomic Context describing neighboring genes Neighboring gene MAM domain containing 4 Neighboring gene endothelial differentiation related factor 1 Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene complement C8 gamma chain

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_013377495.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

Genomic

  1. NC_066380.1 Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

    Range
    11698257..11724346
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035571179.2 → XP_035427072.1  TNF receptor-associated factor 2 isoform X1

    Conserved Domains (4) summary
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:366 → 529
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:301 → 361
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  2. XM_035571181.2 → XP_035427074.1  TNF receptor-associated factor 2 isoform X1

    Conserved Domains (4) summary
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:366 → 529
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:301 → 361
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  3. XM_035571183.2 → XP_035427076.1  TNF receptor-associated factor 2 isoform X1

    Conserved Domains (4) summary
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:366 → 529
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:301 → 361
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  4. XM_035571180.2 → XP_035427073.1  TNF receptor-associated factor 2 isoform X1

    Related
    ENSACYP00000021973.1
    Conserved Domains (4) summary
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:366 → 529
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:301 → 361
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  5. XM_035571185.2 → XP_035427078.1  TNF receptor-associated factor 2 isoform X2

    Related
    ENSACYP00000021949.1
    Conserved Domains (4) summary
    pfam02176
    Location:124 → 181
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:312 → 475
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:247 → 307
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  6. XM_035571186.2 → XP_035427079.1  TNF receptor-associated factor 2 isoform X2

    Conserved Domains (4) summary
    pfam02176
    Location:124 → 181
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:312 → 475
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:247 → 307
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  7. XM_050714667.1 → XP_050570624.1  TNF receptor-associated factor 2 isoform X1

  8. XM_050714670.1 → XP_050570627.1  TNF receptor-associated factor 2 isoform X3

  9. XM_050714669.1 → XP_050570626.1  TNF receptor-associated factor 2 isoform X2

  10. XM_035571189.2 → XP_035427082.1  TNF receptor-associated factor 2 isoform X3

    Conserved Domains (4) summary
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:366 → 411
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:301 → 361
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  11. XM_035571187.1 → XP_035427080.1  TNF receptor-associated factor 2 isoform X2

    Related
    ENSACYP00000021939.1, ENSACYT00000023862.1
    Conserved Domains (4) summary
    pfam02176
    Location:124 → 181
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:312 → 475
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:247 → 307
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain

  12. XM_035571184.1 → XP_035427077.1  TNF receptor-associated factor 2 isoform X1

    Conserved Domains (4) summary
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:366 → 529
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:301 → 361
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
Nucleotide Protein
Heading Accession and Version

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