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LOC118103209 insulin receptor substrate 2 [ Hippoglossus stenolepis (Pacific halibut) ]

Gene ID: 118103209, updated on 8-May-2024

Summary

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Gene symbol
LOC118103209
Gene description
insulin receptor substrate 2
Locus tag
HST_G00227390
See related
EnsemblRapid:ENSHSTG00010008283
Gene type
protein coding
RefSeq status
MODEL
Organism
Hippoglossus stenolepis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Pleuronectidae; Hippoglossus
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Genomic context

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See LOC118103209 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
4
Annotation release Status Assembly Chr Location
101 current HSTE1.2 (GCF_022539355.2) 24 NC_061506.1 (2604376..2614951)
100 previous assembly IPHC_HiSten_1.0 (GCF_013339905.1) 24 NC_048950.1 (2607755..2618400)

Chromosome 24 - NC_061506.1Genomic Context describing neighboring genes Neighboring gene thioredoxin domain containing 16 Neighboring gene G protein-coupled receptor 137c Neighboring gene ligase IV, DNA, ATP-dependent Neighboring gene NALCN channel auxiliary factor 1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables insulin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin receptor substrate 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Hippoglossus stenolepis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HSTE1.2 Primary Assembly

Genomic

  1. NC_061506.1 Reference HSTE1.2 Primary Assembly

    Range
    2604376..2614951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035149901.2 → XP_035005792.1  insulin receptor substrate 2 isoform X2

    Conserved Domains (2) summary
    cd01204
    Location:151 → 254
    PTB_IRS; Insulin receptor substrate phosphotyrosine-binding domain (PTBi)
    cd01257
    Location:17 → 122
    PH_IRS; Insulin receptor substrate (IRS) pleckstrin homology (PH) domain

  2. XM_035149900.2 → XP_035005791.1  insulin receptor substrate 2 isoform X1

    Conserved Domains (2) summary
    cd01204
    Location:151 → 254
    PTB_IRS; Insulin receptor substrate phosphotyrosine-binding domain (PTBi)
    cd01257
    Location:17 → 122
    PH_IRS; Insulin receptor substrate (IRS) pleckstrin homology (PH) domain

  3. XM_035149902.2 → XP_035005793.1  insulin receptor substrate 2 isoform X3

    Related
    ENSHSTP00010018022.1, ENSHSTT00010020150.1
    Conserved Domains (2) summary
    cd01204
    Location:151 → 254
    PTB_IRS; Insulin receptor substrate phosphotyrosine-binding domain (PTBi)
    cd01257
    Location:17 → 122
    PH_IRS; Insulin receptor substrate (IRS) pleckstrin homology (PH) domain
Nucleotide Protein
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