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PTEN phosphatase and tensin homolog [ Zootoca vivipara (common lizard) ]

Gene ID: 118096089, updated on 20-Mar-2024

Summary

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Gene symbol
PTEN
Gene description
phosphatase and tensin homolog
See related
EnsemblRapid:ENSZVIG00000019576
Gene type
protein coding
RefSeq status
MODEL
Organism
Zootoca vivipara
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Zootoca
Orthologs
human mouse all
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Genomic context

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See PTEN in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current rZooViv1.1 (GCF_963506605.1) 5 NC_083280.1 (66276345..66327703, complement)
100 previous assembly UG_Zviv_1 (GCF_011800845.1) Linkage Group LG14 NC_048618.1 (31216676..31271580)

Chromosome 5 - NC_083280.1Genomic Context describing neighboring genes Neighboring gene lysosomal acid lipase/cholesteryl ester hydrolase-like Neighboring gene small ubiquitin-related modifier 3-like Neighboring gene renalase, FAD dependent amine oxidase Neighboring gene uncharacterized LOC118096479 Neighboring gene ATPase family AAA domain containing 1 Neighboring gene 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_963506605.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rZooViv1.1

Genomic

  1. NC_083280.1 Reference rZooViv1.1

    Range
    66276345..66327703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035137353.2 → XP_034993244.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    Related
    ENSZVIP00000026783.1
    Conserved Domains (2) summary
    cd14509
    Location:24 → 181
    PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
    pfam10409
    Location:188 → 350
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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