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PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [ Zootoca vivipara (common lizard) ]

Gene ID: 118080645, updated on 20-Mar-2024

Summary

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Gene symbol
PFKFB4
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
See related
EnsemblRapid:ENSZVIG00000014419
Gene type
protein coding
RefSeq status
MODEL
Organism
Zootoca vivipara
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Laterata; Lacertibaenia; Lacertidae; Zootoca
Orthologs
human mouse all
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Genomic context

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See PFKFB4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_10 current rZooViv1.1 (GCF_963506605.1) 2 NC_083277.1 (49815382..49897114)
100 previous assembly UG_Zviv_1 (GCF_011800845.1) Linkage Group LG2 NC_048606.1 (71342260..71425218, complement)

Chromosome 2 - NC_083277.1Genomic Context describing neighboring genes Neighboring gene shisa family member 5 Neighboring gene actin nucleation-promoting factor WASL-like Neighboring gene protein kinase C delta Neighboring gene RFT1 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_963506605.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rZooViv1.1

Genomic

  1. NC_083277.1 Reference rZooViv1.1

    Range
    49815382..49897114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035106180.2 → XP_034962071.2  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X4

  2. XM_060271498.1 → XP_060127481.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X3

  3. XM_035106178.2 → XP_034962069.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X2

    Conserved Domains (2) summary
    pfam00300
    Location:254 → 440
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:32 → 251
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_035106177.2 → XP_034962068.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1

    Related
    ENSZVIP00000019486.1
    Conserved Domains (2) summary
    pfam00300
    Location:254 → 440
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:32 → 251
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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