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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Mirounga leonina (Southern elephant seal) ]

Gene ID: 118000485, updated on 20-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Locus tag
GH733_019042
See related
EnsemblRapid:ENSMLOG00005016946
Gene type
protein coding
RefSeq status
MODEL
Organism
Mirounga leonina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Mirounga
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current KU_Mleo_1.0 (GCF_011800145.1) Unplaced Scaffold NW_023270143.1 (1748833..1859021, complement)

NW_023270143.1Genomic Context describing neighboring genes Neighboring gene melanoma-associated antigen D2 Neighboring gene small nucleolar RNA SNORA11 Neighboring gene trophinin-like Neighboring gene small nucleolar RNA SNORA11 Neighboring gene small EDRK-rich factor 2-like Neighboring gene uncharacterized LOC118001066 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene 5'-aminolevulinate synthase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023270143 Unplaced Scaffold Reference KU_Mleo_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mirounga leonina Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference KU_Mleo_1.0 Primary Assembly

Genomic

  1. NW_023270143.1 Reference KU_Mleo_1.0 Primary Assembly

    Range
    1748833..1859021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034990545.1 → XP_034846436.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X5

    Related
    ENSMLOP00005024751.1, ENSMLOT00005027880.1
    Conserved Domains (2) summary
    pfam00300
    Location:241 → 427
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:7 → 238
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_034990616.1 → XP_034846507.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X6

    Conserved Domains (2) summary
    pfam00300
    Location:232 → 418
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 229
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_034990470.1 → XP_034846361.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    Conserved Domains (2) summary
    pfam00300
    Location:242 → 428
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 239
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_034990394.1 → XP_034846285.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    Conserved Domains (2) summary
    pfam00300
    Location:245 → 431
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 242
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_034990694.1 → XP_034846585.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X7

    Conserved Domains (2) summary
    pfam00300
    Location:264 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 261
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_034990259.1 → XP_034846150.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:264 → 450
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 261
    6PF2K; 6-phosphofructo-2-kinase

  7. XM_034990322.1 → XP_034846213.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    Related
    ENSMLOP00005024794.1, ENSMLOT00005027932.1
    Conserved Domains (2) summary
    pfam00300
    Location:254 → 440
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 251
    6PF2K; 6-phosphofructo-2-kinase

  8. XM_034990766.1 → XP_034846657.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X8

    Conserved Domains (2) summary
    pfam00300
    Location:264 → 376
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:30 → 261
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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