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tlr18 toll-like receptor 18 [ Cyclopterus lumpus (lumpfish) ]

Gene ID: 117745125, updated on 19-Mar-2024

Summary

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Gene symbol
tlr18
Gene description
toll-like receptor 18
See related
Ensembl:ENSCLMG00005007255
Gene type
protein coding
RefSeq status
MODEL
Organism
Cyclopterus lumpus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Cottioidei; Cottales; Cyclopteridae; Cyclopterus
Orthologs
zebrafish all
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Genomic context

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See tlr18 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
4
Annotation release Status Assembly Chr Location
100 current fCycLum1.pri (GCF_009769545.1) 16 NC_046981.1 (2405126..2416371, complement)

Chromosome 16 - NC_046981.1Genomic Context describing neighboring genes Neighboring gene PR domain containing 1a, with ZNF domain Neighboring gene uncharacterized LOC117745133 Neighboring gene S100 calcium binding protein A1 Neighboring gene leucine rich repeat and Ig domain containing 4b

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046981.1 Chromosome 16 Reference fCycLum1.pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
toll-like receptor 18

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cyclopterus lumpus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fCycLum1.pri

Genomic

  1. NC_046981.1 Reference fCycLum1.pri

    Range
    2405126..2416371 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034553208.1 → XP_034409099.1  toll-like receptor 18 isoform X2

    UniProtKB/TrEMBL
    A0A8C2X4W8
    Related
    ENSCLMP00005013699.1, ENSCLMT00005014639.1
    Conserved Domains (6) summary
    smart00255
    Location:664 → 803
    TIR; Toll - interleukin 1 - resistance
    COG4886
    Location:221 → 530
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:61 → 84
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:373 → 400
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:59 → 202
    internalin_A; class 1 internalin InlA
    pfam13855
    Location:92 → 142
    LRR_8; Leucine rich repeat

  2. XM_034553207.1 → XP_034409098.1  toll-like receptor 18 isoform X1

    Conserved Domains (6) summary
    smart00255
    Location:680 → 819
    TIR; Toll - interleukin 1 - resistance
    COG4886
    Location:237 → 546
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:77 → 100
    LRR_1; leucine-rich repeat [structural motif]
    sd00033
    Location:389 → 416
    LRR_RI; leucine-rich repeat [structural motif]
    NF033189
    Location:75 → 218
    internalin_A; class 1 internalin InlA
    pfam13855
    Location:108 → 158
    LRR_8; Leucine rich repeat
Nucleotide Protein
Heading Accession and Version

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