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SHMT1 serine hydroxymethyltransferase 1 [ Pantherophis guttatus ]

Gene ID: 117679512, updated on 19-Mar-2024

Summary

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Gene symbol
SHMT1
Gene description
serine hydroxymethyltransferase 1
See related
EnsemblRapid:ENSPGUG00005011843
Gene type
protein coding
RefSeq status
MODEL
Organism
Pantherophis guttatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Colubrinae; Pantherophis
Orthologs
human mouse all
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Genomic context

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See SHMT1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_10 current CU_Pguttatus_1 (GCF_029531705.1) Unplaced Scaffold NW_026844103.1 (3719770..3728188, complement)
100 previous assembly UNIGE_PanGut_3.0 (GCF_001185365.1) Unplaced Scaffold NW_023010883.1 (1083755..1092178)

NW_026844103.1Genomic Context describing neighboring genes Neighboring gene mitochondrial elongation factor 2 Neighboring gene DNA topoisomerase III alpha Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene chemerin-like receptor 1 Neighboring gene phosphoribosyl pyrophosphate synthetase associated protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine hydroxymethyltransferase, cytosolic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029531705.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CU_Pguttatus_1

Genomic

  1. NW_026844103.1 Reference CU_Pguttatus_1

    Range
    3719770..3728188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034441507.2 → XP_034297398.1  serine hydroxymethyltransferase, cytosolic isoform X2

    UniProtKB/TrEMBL
    A0A6P9DPH2
    Related
    ENSPGUP00005016847.1
    Conserved Domains (1) summary
    PLN03226
    Location:26 → 484
    PLN03226; serine hydroxymethyltransferase; Provisional

  2. XM_034441506.2 → XP_034297397.1  serine hydroxymethyltransferase, cytosolic isoform X1

    UniProtKB/TrEMBL
    A0A6P9DNI8
    Conserved Domains (1) summary
    PLN03226
    Location:26 → 521
    PLN03226; serine hydroxymethyltransferase; Provisional
Nucleotide Protein
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