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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Pantherophis guttatus ]

Gene ID: 117676837, updated on 10-Oct-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
EnsemblRapid:ENSPGUG00005007687
Gene type
protein coding
RefSeq status
MODEL
Organism
Pantherophis guttatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Colubrinae; Pantherophis
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_10 current CU_Pguttatus_1 (GCF_029531705.1) Unplaced Scaffold NW_026843744.1 (1422018..1520781)
100 previous assembly UNIGE_PanGut_3.0 (GCF_001185365.1) Unplaced Scaffold NW_023010861.1 (605438..693875)

NW_026843744.1Genomic Context describing neighboring genes Neighboring gene THAP domain containing 7 Neighboring gene RNA binding motif protein 17 Neighboring gene protein kinase C theta Neighboring gene Scm like with four mbt domains 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029531705.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CU_Pguttatus_1

Genomic

  1. NW_026843744.1 Reference CU_Pguttatus_1

    Range
    1422018..1520781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034436641.2 → XP_034292532.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

    UniProtKB/TrEMBL
    A0A6P9D9V0, A0A6P9DJX3
    Related
    ENSPGUP00005010768.1
    Conserved Domains (2) summary
    pfam00300
    Location:229 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:4 → 226
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_034436639.2 → XP_034292530.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    UniProtKB/TrEMBL
    A0A6P9DJX3, A0A6P9DMS3
    Conserved Domains (2) summary
    pfam00300
    Location:250 → 436
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:24 → 247
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_060686246.1 → XP_060542229.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

  4. XM_034436638.2 → XP_034292529.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    UniProtKB/TrEMBL
    A0A6P9DC04, A0A6P9DJX3
    Related
    ENSPGUP00005010852.1
    Conserved Domains (2) summary
    pfam00300
    Location:229 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:6 → 226
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_034436637.2 → XP_034292528.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    UniProtKB/TrEMBL
    A0A6P9D8M0, A0A6P9DJX3
    Conserved Domains (2) summary
    pfam00300
    Location:229 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:6 → 226
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_034436642.2 → XP_034292533.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

    UniProtKB/TrEMBL
    A0A6P9D8M6, A0A6P9DJX3
    Conserved Domains (2) summary
    pfam00300
    Location:229 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:6 → 226
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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