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PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 [ Pantherophis guttatus ]

Gene ID: 117675456, updated on 19-Mar-2024

Summary

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Gene symbol
PFKFB1
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
See related
EnsemblRapid:ENSPGUG00005004663
Gene type
protein coding
RefSeq status
MODEL
Organism
Pantherophis guttatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Colubrinae; Pantherophis
Orthologs
human mouse all
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Genomic context

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See PFKFB1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_10 current CU_Pguttatus_1 (GCF_029531705.1) Unplaced Scaffold NW_026844096.1 (2678293..2697196)
100 previous assembly UNIGE_PanGut_3.0 (GCF_001185365.1) Unplaced Scaffold NW_023010833.1 (2442681..2461583)

NW_026844096.1Genomic Context describing neighboring genes Neighboring gene prickle planar cell polarity protein 3 Neighboring gene 5'-aminolevulinate synthase 2 Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 2 Neighboring gene non-structural maintenance of chromosomes element 3 homolog Neighboring gene inter-alpha-trypsin inhibitor heavy chain family member 6 Neighboring gene PHD finger protein 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029531705.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CU_Pguttatus_1

Genomic

  1. NW_026844096.1 Reference CU_Pguttatus_1

    Range
    2678293..2697196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034434098.2 → XP_034289989.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P9D296
    Related
    ENSPGUP00005006390.1
    Conserved Domains (2) summary
    pfam00300
    Location:240 → 426
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:15 → 237
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_034434097.2 → XP_034289988.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P9D296
    Conserved Domains (2) summary
    pfam00300
    Location:240 → 426
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:15 → 237
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_034434096.2 → XP_034289987.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P9D2T4
    Conserved Domains (2) summary
    pfam00300
    Location:253 → 439
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 250
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_034434100.2 → XP_034289991.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X4

    UniProtKB/TrEMBL
    A0A6P9DCR8
    Conserved Domains (2) summary
    pfam00300
    Location:253 → 439
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:28 → 250
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_034434099.2 → XP_034289990.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P9DF44
    Conserved Domains (2) summary
    pfam00300
    Location:212 → 398
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 209
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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