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HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Pantherophis guttatus ]

Gene ID: 117663350, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCL
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
See related
EnsemblRapid:ENSPGUG00005011533
Gene type
protein coding
RefSeq status
MODEL
Organism
Pantherophis guttatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Colubrinae; Pantherophis
Orthologs
human mouse all
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Genomic context

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See HMGCL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current CU_Pguttatus_1 (GCF_029531705.1) Unplaced Scaffold NW_026844034.1 (11365266..11385501, complement)
100 previous assembly UNIGE_PanGut_3.0 (GCF_001185365.1) Unplaced Scaffold NW_023010715.1 (11179252..11200176, complement)

NW_026844034.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117663347 Neighboring gene uncharacterized LOC117663348 Neighboring gene lysophospholipase 2 Neighboring gene UDP-galactose-4-epimerase Neighboring gene alpha-L-fucosidase 1 Neighboring gene uncharacterized LOC117663354 Neighboring gene cannabinoid receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029531705.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CU_Pguttatus_1

Genomic

  1. NW_026844034.1 Reference CU_Pguttatus_1

    Range
    11365266..11385501 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034413450.2 → XP_034269341.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A6P9BMB2
    Related
    ENSPGUP00005016384.1
    Conserved Domains (1) summary
    PLN02746
    Location:47 → 342
    PLN02746; hydroxymethylglutaryl-CoA lyase

  2. XM_034413451.2 → XP_034269342.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A6P9BDK8
    Related
    ENSPGUP00005016392.1
    Conserved Domains (1) summary
    PLN02746
    Location:27 → 322
    PLN02746; hydroxymethylglutaryl-CoA lyase

  3. XM_034413452.2 → XP_034269343.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A6P9BEU7
    Related
    ENSPGUP00005016413.1
    Conserved Domains (1) summary
    PLN02746
    Location:25 → 320
    PLN02746; hydroxymethylglutaryl-CoA lyase
Nucleotide Protein
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