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LOC117452000 TNF receptor-associated factor 2-like [ Pseudochaenichthys georgianus (South Georgia icefish) ]

Gene ID: 117452000, updated on 14-Dec-2023

Summary

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Gene symbol
LOC117452000
Gene description
TNF receptor-associated factor 2-like
See related
EnsemblRapid:ENSPGEG00000002597
Gene type
protein coding
RefSeq status
MODEL
Organism
Pseudochaenichthys georgianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Notothenioidei; Channichthyidae; Pseudochaenichthys
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Genomic context

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See LOC117452000 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
10
Annotation release Status Assembly Chr Location
100 current fPseGeo1.1 (GCF_902827115.1) 9 NC_047511.1 (4158610..4175729, complement)

Chromosome 9 - NC_047511.1Genomic Context describing neighboring genes Neighboring gene beta-1,3-galactosyltransferase 2 Neighboring gene tenascin C Neighboring gene uncharacterized LOC117452153 Neighboring gene rab-like protein 6 Neighboring gene IMP U3 small nucleolar ribonucleoprotein 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_047511.1 Chromosome 9 Reference fPseGeo1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pseudochaenichthys georgianus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fPseGeo1.1

Genomic

  1. NC_047511.1 Reference fPseGeo1.1

    Range
    4158610..4175729 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034090402.1 → XP_033946293.1  TNF receptor-associated factor 2-like isoform X2

    Related
    ENSPGEP00000005525.1, ENSPGET00000005794.1
    Conserved Domains (6) summary
    COG5432
    Location:28 → 186
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    TIGR02168
    Location:229 → 385
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:381 → 541
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:314 → 373
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl40617
    Location:178 → 216
    zf-TRAF; TRAF-type zinc finger

  2. XM_034090401.1 → XP_033946292.1  TNF receptor-associated factor 2-like isoform X1

    Related
    ENSPGEP00000005523.1, ENSPGET00000005792.1
    Conserved Domains (6) summary
    COG5432
    Location:28 → 186
    RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    TIGR02168
    Location:254 → 410
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
    cl02446
    Location:406 → 566
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:339 → 398
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl40617
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
Nucleotide Protein
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