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map2k5 mitogen-activated protein kinase kinase 5 [ Acipenser ruthenus (sterlet) ]

Gene ID: 117429614, updated on 19-Mar-2024

Summary

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Gene symbol
map2k5
Gene description
mitogen-activated protein kinase kinase 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Acipenser ruthenus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Chondrostei; Acipenseriformes; Acipenseridae; Acipenser
Orthologs
human zebrafish all
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Genomic context

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See map2k5 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2023_08 current fAciRut3.2 maternal haplotype (GCF_902713425.1) 24 NC_081212.1 (27113342..27184101)
101 previous assembly ASM1064508v1 (GCF_010645085.1) 27 NC_048349.1 (16130234..16200343, complement)

Chromosome 24 - NC_081212.1Genomic Context describing neighboring genes Neighboring gene IQ domain-containing protein H-like Neighboring gene uncharacterized protein C15orf61-like Neighboring gene SKI family transcriptional corepressor 1a Neighboring gene E3 SUMO-protein ligase PIAS1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity mitogen-activated protein kinase kinase 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_902713425.1-RS_2023_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fAciRut3.2 maternal haplotype Primary Assembly

Genomic

  1. NC_081212.1 Reference fAciRut3.2 maternal haplotype Primary Assembly

    Range
    27113342..27184101
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034049330.3 → XP_033905221.1  dual specificity mitogen-activated protein kinase kinase 5

    Conserved Domains (2) summary
    cd06395
    Location:17 → 107
    PB1_Map2k5; PB1 domain is essential part of the mitogen-activated protein kinase kinase 5 (Map2k5, alias MEK5) one of the key member of the signaling kinases cascade which involved in angiogenesis and early cardiovascular development. The PB1 domain of Map2k5 ...
    cd06619
    Location:164 → 442
    PKc_MKK5; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 5
Nucleotide Protein
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