U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FASN fatty acid synthase [ Geotrypetes seraphini ]

Gene ID: 117367606, updated on 19-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
FASN
Gene description
fatty acid synthase
Gene type
protein coding
RefSeq status
MODEL
Organism
Geotrypetes seraphini
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Geotrypetes
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See FASN in Genome Data Viewer
Location:
chromosome: 10
Exon count:
43
Annotation release Status Assembly Chr Location
100 current aGeoSer1.1 (GCF_902459505.1) 10 NC_047093.1 (766972..984528)

Chromosome 10 - NC_047093.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 16 member 3 Neighboring gene coiled-coil domain containing 57 Neighboring gene dihydrouridine synthase 1 like Neighboring gene G protein pathway suppressor 1 Neighboring gene RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_047093.1 Chromosome 10 Reference aGeoSer1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty acid synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphopantetheine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
fatty acid synthase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Geotrypetes seraphini Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aGeoSer1.1 Primary Assembly

Genomic

  1. NC_047093.1 Reference aGeoSer1.1 Primary Assembly

    Range
    766972..984528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033960321.1 → XP_033816212.1  fatty acid synthase

    UniProtKB/TrEMBL
    A0A6P8SDD9
    Conserved Domains (10) summary
    cd08954
    Location:1881 → 2117
    KR_1_FAS_SDR_x; beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs
    smart00823
    Location:2123 → 2185
    PKS_PP; Phosphopantetheine attachment site
    smart00829
    Location:1569 → 1859
    PKS_ER; Enoylreductase
    cd00833
    Location:2 → 404
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam00698
    Location:492 → 809
    Acyl_transf_1; Acyl transferase domain
    pfam08242
    Location:1255 → 1348
    Methyltransf_12; Methyltransferase domain
    pfam16197
    Location:362 → 471
    KAsynt_C_assoc; Ketoacyl-synthetase C-terminal extension
    cl00509
    Location:874 → 1061
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
    cl21454
    Location:1322 → 1529
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    cl21494
    Location:2248 → 2505
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.