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CAPN3 calpain 3 [ Geotrypetes seraphini ]

Gene ID: 117364048, updated on 19-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Geotrypetes seraphini
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Geotrypetes
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
24
Annotation release Status Assembly Chr Location
100 current aGeoSer1.1 (GCF_902459505.1) 7 NC_047090.1 (117697545..117799373)

Chromosome 7 - NC_047090.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene glucosidase alpha, neutral C Neighboring gene zinc finger protein 106 Neighboring gene U4 spliceosomal RNA Neighboring gene inositol-trisphosphate 3-kinase A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_047090.1 Chromosome 7 Reference aGeoSer1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Geotrypetes seraphini Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aGeoSer1.1 Primary Assembly

Genomic

  1. NC_047090.1 Reference aGeoSer1.1 Primary Assembly

    Range
    117697545..117799373
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033952814.1 → XP_033808705.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A6P8RSY1
    Conserved Domains (4) summary
    cd16190
    Location:639 → 807
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 408
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:429 → 567
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:576 → 600
    Calpain_u2; Unstructured region on Calpain-3

  2. XM_033952813.1 → XP_033808704.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A6P8RT71
    Conserved Domains (4) summary
    cd16190
    Location:645 → 813
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 408
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:429 → 567
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:576 → 606
    Calpain_u2; Unstructured region on Calpain-3

  3. XM_033952815.1 → XP_033808706.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A6P8RVB9
    Conserved Domains (3) summary
    cd16190
    Location:602 → 770
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:70 → 408
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:429 → 567
    Calpain_III; Calpain large subunit, domain III
Nucleotide Protein
Heading Accession and Version

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