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ALOX12 arachidonate 12-lipoxygenase, 12S type [ Geotrypetes seraphini ]

Gene ID: 117350677, updated on 19-Mar-2024

Summary

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Gene symbol
ALOX12
Gene description
arachidonate 12-lipoxygenase, 12S type
Gene type
protein coding
RefSeq status
MODEL
Organism
Geotrypetes seraphini
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Gymnophiona; Geotrypetes
Orthologs
human mouse all
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Genomic context

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See ALOX12 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
14
Annotation release Status Assembly Chr Location
100 current aGeoSer1.1 (GCF_902459505.1) 16 NC_047099.1 (17269573..17369282)

Chromosome 16 - NC_047099.1Genomic Context describing neighboring genes Neighboring gene protein FAM122A-like Neighboring gene chromosome 16 C17orf49 homolog Neighboring gene proline, glutamate and leucine rich protein 1 Neighboring gene ribonuclease K Neighboring gene arrestin beta 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_047099.1 Chromosome 16 Reference aGeoSer1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12S-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Geotrypetes seraphini Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aGeoSer1.1 Primary Assembly

Genomic

  1. NC_047099.1 Reference aGeoSer1.1 Primary Assembly

    Range
    17269573..17369282
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033925159.1 → XP_033781050.1  arachidonate 12-lipoxygenase, 12S-type

    UniProtKB/TrEMBL
    A0A6P8PI35
    Conserved Domains (2) summary
    cd01753
    Location:2 → 114
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:164 → 660
    Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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