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Smurf SMAD specific E3 ubiquitin protein ligase [ Bombus bifarius ]

Gene ID: 117211752, updated on 10-Oct-2024

Summary

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Gene symbol
Smurf
Gene description
SMAD specific E3 ubiquitin protein ligase
See related
EnsemblRapid:ENSBBSG00000008811
Gene type
protein coding
RefSeq status
MODEL
Organism
Bombus bifarius
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea; Anthophila; Apidae; Bombus; Pyrobombus
Orthologs
fruit fly honey bee all
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Genomic context

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See Smurf in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
100 current Bbif_JDL3187 (GCF_011952205.1) Unplaced Scaffold NW_022884356.1 (3902014..3910830, complement)

NW_022884356.1Genomic Context describing neighboring genes Neighboring gene Multiplexin Neighboring gene uncharacterized LOC117211910 Neighboring gene uncharacterized LOC117211917 Neighboring gene THO complex 1-like protein Hpr1 Neighboring gene Mitochondrial rRNA methyltransferase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_022884356 Unplaced Scaffold Reference Bbif_JDL3187

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase SMURF1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bombus bifarius Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bbif_JDL3187

Genomic

  1. NW_022884356.1 Reference Bbif_JDL3187

    Range
    3902014..3910830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033455992.1 → XP_033311883.1  E3 ubiquitin-protein ligase SMURF1 isoform X2

    UniProtKB/TrEMBL
    A0A6P8MTZ0
    Related
    ENSBBSP00000011564.1, ENSBBST00000022220.1
    Conserved Domains (4) summary
    cd08382
    Location:14 → 137
    C2_Smurf-like; C2 domain present in Smad ubiquitination-related factor (Smurf)-like proteins
    smart00456
    Location:397 → 429
    WW; Domain with 2 conserved Trp (W) residues
    cd00078
    Location:546 → 902
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam00397
    Location:169 → 198
    WW; WW domain

  2. XM_033455979.1 → XP_033311870.1  E3 ubiquitin-protein ligase SMURF1 isoform X1

    UniProtKB/TrEMBL
    A0A6P8NBI6
    Conserved Domains (4) summary
    cd08382
    Location:14 → 137
    C2_Smurf-like; C2 domain present in Smad ubiquitination-related factor (Smurf)-like proteins
    smart00456
    Location:397 → 429
    WW; Domain with 2 conserved Trp (W) residues
    cd00078
    Location:547 → 903
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam00397
    Location:169 → 198
    WW; WW domain

  3. XM_033455974.1 → XP_033311865.1  E3 ubiquitin-protein ligase SMURF1 isoform X1

    UniProtKB/TrEMBL
    A0A6P8NBI6
    Conserved Domains (4) summary
    cd08382
    Location:14 → 137
    C2_Smurf-like; C2 domain present in Smad ubiquitination-related factor (Smurf)-like proteins
    smart00456
    Location:397 → 429
    WW; Domain with 2 conserved Trp (W) residues
    cd00078
    Location:547 → 903
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam00397
    Location:169 → 198
    WW; WW domain

  4. XM_033455965.1 → XP_033311856.1  E3 ubiquitin-protein ligase SMURF1 isoform X1

    UniProtKB/TrEMBL
    A0A6P8NBI6
    Related
    ENSBBSP00000011558.1, ENSBBST00000022222.1
    Conserved Domains (4) summary
    cd08382
    Location:14 → 137
    C2_Smurf-like; C2 domain present in Smad ubiquitination-related factor (Smurf)-like proteins
    smart00456
    Location:397 → 429
    WW; Domain with 2 conserved Trp (W) residues
    cd00078
    Location:547 → 903
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam00397
    Location:169 → 198
    WW; WW domain

RNA

  1. XR_004488321.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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