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TJP2 tight junction protein 2 [ Trachypithecus francoisi (Francois's langur) ]

Gene ID: 117098495, updated on 19-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
EnsemblRapid:ENSTFRG00000007477
Gene type
protein coding
RefSeq status
MODEL
Organism
Trachypithecus francoisi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Trachypithecus
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current Tfra_2.0 (GCF_009764315.1) Unplaced Scaffold NW_022681461.1 (28521980..28662602, complement)

NW_022681461.1Genomic Context describing neighboring genes Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene uncharacterized LOC117099324 Neighboring gene frataxin Neighboring gene protein kinase cAMP-activated catalytic subunit gamma

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_022681461 Unplaced Scaffold Reference Tfra_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Trachypithecus francoisi Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tfra_2.0 Primary Assembly

Genomic

  1. NW_022681461.1 Reference Tfra_2.0 Primary Assembly

    Range
    28521980..28662602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033237145.1 → XP_033093036.1  tight junction protein ZO-2 isoform X4

    Related
    ENSTFRP00000010854.1, ENSTFRT00000013589.1
    Conserved Domains (5) summary
    cd12027
    Location:567 → 629
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:663 → 842
    GuKc; Guanylate kinase homologues
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:144 → 238
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:262 → 345
    PDZ; PDZ domain (Also known as DHR or GLGF)

  2. XM_033237147.1 → XP_033093038.1  tight junction protein ZO-2 isoform X6

    Conserved Domains (5) summary
    cd12027
    Location:590 → 652
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:686 → 865
    GuKc; Guanylate kinase homologues
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:167 → 261
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:285 → 368
    PDZ; PDZ domain (Also known as DHR or GLGF)

  3. XM_033237143.1 → XP_033093034.1  tight junction protein ZO-2 isoform X2

    Related
    ENSTFRP00000011080.1, ENSTFRT00000013873.1
    Conserved Domains (5) summary
    cd12027
    Location:590 → 652
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:686 → 865
    GuKc; Guanylate kinase homologues
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:167 → 261
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:285 → 368
    PDZ; PDZ domain (Also known as DHR or GLGF)

  4. XM_033237142.1 → XP_033093033.1  tight junction protein ZO-2 isoform X1

    Related
    ENSTFRP00000011000.1, ENSTFRT00000013768.1
    Conserved Domains (5) summary
    cd12027
    Location:590 → 652
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:686 → 865
    GuKc; Guanylate kinase homologues
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:167 → 261
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:285 → 368
    PDZ; PDZ domain (Also known as DHR or GLGF)

  5. XM_033237148.1 → XP_033093039.1  tight junction protein ZO-2 isoform X7

    Related
    ENSTFRP00000010925.1, ENSTFRT00000013679.1
    Conserved Domains (5) summary
    cd12027
    Location:594 → 656
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:690 → 869
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:171 → 265
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:289 → 372
    PDZ; PDZ domain (Also known as DHR or GLGF)

  6. XM_033237146.1 → XP_033093037.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (5) summary
    cd12027
    Location:594 → 656
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:690 → 869
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:171 → 265
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:289 → 372
    PDZ; PDZ domain (Also known as DHR or GLGF)

  7. XM_033237144.1 → XP_033093035.1  tight junction protein ZO-2 isoform X3

    Related
    ENSTFRP00000011153.1, ENSTFRT00000013967.1
    Conserved Domains (5) summary
    cd12027
    Location:594 → 656
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:690 → 869
    GuKc; Guanylate kinase homologues
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:171 → 265
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
    pfam00595
    Location:289 → 372
    PDZ; PDZ domain (Also known as DHR or GLGF)
Nucleotide Protein
Heading Accession and Version

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