LOC117038784 CRISPRi-FlowFISH-validated WDR83OS regulatory element [ Homo sapiens (human) ]

Gene ID: 117038784, discontinued on 17-Nov-2022

Summary

Gene symbol: LOC117038784
Gene description: CRISPRi-FlowFISH-validated WDR83OS regulatory element
Gene type: biological region
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary: This genomic region was predicted to be an enhancer based on an activity-by-contact (ABC) model that predicts enhancer-gene connections, where the putative enhancer strength is measured by DNase I hypersensitivity and H3K27 acetylation, and the contact frequency by Hi-C. It was validated as a positively-acting cis-regulatory element for the WDR83OS (WD repeat domain 83 opposite strand) gene based on CRISPR/Cas9-mediated perturbation (CRISPRi-FlowFISH method) in K562 erythroleukemia cells. [provided by RefSeq, Mar 2020]
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Annotation release	Status	Assembly	Chr	Location
110	latest, but not current	GRCh38.p14 (GCF_000001405.40)	19	NC_000019.10 (12681111..12681611)
110	latest, but not current	T2T-CHM13v2.0 (GCF_009914755.1)	19	NC_060943.1 (12805611..12806111)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	19	NC_000019.9 (12791925..12792425)