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HK1 hexokinase 1 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117036227, updated on 19-Jun-2024

Summary

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Gene symbol
HK1
Gene description
hexokinase 1
See related
EnsemblRapid:ENSRFEG00010009380
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See HK1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 16 NC_046299.1 (47681378..47746007)

Chromosome 16 - NC_046299.1Genomic Context describing neighboring genes Neighboring gene Suv3 like RNA helicase Neighboring gene hexokinase domain containing 1 Neighboring gene tachykinin receptor 2 Neighboring gene tetraspanin 15 Neighboring gene peptidyl-prolyl cis-trans isomerase FKBP1A-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046299.1 Chromosome 16 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables D-glucose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables glucokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mannokinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose 6-phosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hexokinase-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046299.1 Reference mRhiFer1_v1.p

    Range
    47681378..47746007
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033130988.1 → XP_032986879.1  hexokinase-1 isoform X2

    UniProtKB/TrEMBL
    A0A671EKI7, A0A671EKP6
    Related
    ENSRFEP00010013859.1, ENSRFET00010015156.2
    Conserved Domains (3) summary
    PTZ00107
    Location:21 → 459
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:468 → 666
    Hexokinase_1
    pfam03727
    Location:672 → 906
    Hexokinase_2

  2. XM_033130986.1 → XP_032986877.1  hexokinase-1 isoform X1

    UniProtKB/TrEMBL
    A0A671EKP6, A0A671EU94
    Related
    ENSRFEP00010013892.1, ENSRFET00010015194.2
    Conserved Domains (3) summary
    PTZ00107
    Location:12 → 460
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:469 → 667
    Hexokinase_1
    pfam03727
    Location:673 → 907
    Hexokinase_2

  3. XM_033130989.1 → XP_032986880.1  hexokinase-1 isoform X3

    UniProtKB/TrEMBL
    A0A671EKP6, A0A671ELF2
    Related
    ENSRFEP00010013920.1, ENSRFET00010015224.2
    Conserved Domains (3) summary
    PTZ00107
    Location:4 → 446
    PTZ00107; hexokinase; Provisional
    pfam00349
    Location:455 → 653
    Hexokinase_1
    pfam03727
    Location:659 → 893
    Hexokinase_2
Nucleotide Protein
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