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GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117032175, updated on 30-Mar-2024

Summary

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Gene symbol
GNE
Gene description
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
See related
EnsemblRapid:ENSRFEG00010014157
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See GNE in Genome Data Viewer
Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 12 NC_046295.1 (52260565..52306312, complement)

Chromosome 12 - NC_046295.1Genomic Context describing neighboring genes Neighboring gene GLI pathogenesis related 2 Neighboring gene calicin Neighboring gene clathrin light chain A Neighboring gene ring finger protein 38 Neighboring gene uncharacterized LOC117032583 Neighboring gene maternal embryonic leucine zipper kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046295.1 Chromosome 12 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylmannosamine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables UDP-N-acetylglucosamine 2-epimerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydrolase activity, hydrolyzing O-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in UDP-N-acetylglucosamine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046295.1 Reference mRhiFer1_v1.p

    Range
    52260565..52306312 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033123478.1 → XP_032979369.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1

    UniProtKB/TrEMBL
    A0A671F7W7, A0A671F854
    Conserved Domains (2) summary
    COG1940
    Location:440 → 744
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:42 → 405
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  2. XM_033123479.1 → XP_032979370.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1

    UniProtKB/TrEMBL
    A0A671F7W7, A0A671F854
    Related
    ENSRFEP00010021752.1, ENSRFET00010023672.2
    Conserved Domains (2) summary
    COG1940
    Location:440 → 744
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:42 → 405
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  3. XM_033123480.1 → XP_032979371.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2

    UniProtKB/TrEMBL
    A0A671F813, A0A671F854
    Related
    ENSRFEP00010021639.2, ENSRFET00010023552.2
    Conserved Domains (2) summary
    COG1940
    Location:409 → 713
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

  4. XM_033123481.1 → XP_032979372.1  bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X2

    UniProtKB/TrEMBL
    A0A671F813, A0A671F854
    Related
    ENSRFEP00010021594.2, ENSRFET00010023500.2
    Conserved Domains (2) summary
    COG1940
    Location:409 → 713
    NagC; Sugar kinase of the NBD/HSP70 family, may contain an N-terminal HTH domain [Transcription, Carbohydrate transport and metabolism]
    TIGR03568
    Location:11 → 374
    NeuC_NnaA; UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing

RNA

  1. XR_004424695.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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