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TLE1 TLE family member 1, transcriptional corepressor [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117032095, updated on 30-Mar-2024

Summary

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Gene symbol
TLE1
Gene description
TLE family member 1, transcriptional corepressor
See related
EnsemblRapid:ENSRFEG00010013065
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human all
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Genomic context

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See TLE1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 12 NC_046295.1 (45441965..45526021, complement)

Chromosome 12 - NC_046295.1Genomic Context describing neighboring genes Neighboring gene thiamin pyrophosphokinase 1-like Neighboring gene diamine acetyltransferase 1-like Neighboring gene succinate dehydrogenase cytochrome b560 subunit, mitochondrial-like Neighboring gene Y-box-binding protein 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046295.1 Chromosome 12 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transducin-like enhancer protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046295.1 Reference mRhiFer1_v1.p

    Range
    45441965..45526021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033123273.1 → XP_032979164.1  transducin-like enhancer protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A671F2Q1
    Related
    ENSRFEP00010019866.2, ENSRFET00010021625.2
    Conserved Domains (4) summary
    PHA03247
    Location:253 → 410
    PHA03247; large tegument protein UL36; Provisional
    cd00200
    Location:417 → 701
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:421 → 460
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:3 → 67
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  2. XM_033123271.1 → XP_032979162.1  transducin-like enhancer protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A671F2Q1
    Conserved Domains (4) summary
    PHA03247
    Location:273 → 430
    PHA03247; large tegument protein UL36; Provisional
    cd00200
    Location:437 → 721
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:441 → 480
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:9 → 77
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  3. XM_033123269.1 → XP_032979160.1  transducin-like enhancer protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A671F2Q1, A0A7J7VT06
    Conserved Domains (4) summary
    PHA03247
    Location:329 → 486
    PHA03247; large tegument protein UL36; Provisional
    cd00200
    Location:493 → 777
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:497 → 536
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:9 → 143
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  4. XM_033123270.1 → XP_032979161.1  transducin-like enhancer protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A671F2K5, A0A671F2Q1
    Related
    ENSRFEP00010019824.1, ENSRFET00010021576.2
    Conserved Domains (4) summary
    PHA03247
    Location:319 → 476
    PHA03247; large tegument protein UL36; Provisional
    cd00200
    Location:483 → 767
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:487 → 526
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:9 → 133
    TLE_N; Groucho/TLE N-terminal Q-rich domain
Nucleotide Protein
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