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LARGE1 LARGE xylosyl- and glucuronyltransferase 1 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117028586, updated on 30-Mar-2024

Summary

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Gene symbol
LARGE1
Gene description
LARGE xylosyl- and glucuronyltransferase 1
See related
EnsemblRapid:ENSRFEG00010006902
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See LARGE1 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 10 NC_046293.1 (11985978..12480371)

Chromosome 10 - NC_046293.1Genomic Context describing neighboring genes Neighboring gene ribosome biogenesis protein NSA2 homolog Neighboring gene mediator of RNA polymerase II transcription subunit 28-like Neighboring gene small nucleolar RNA SNORA76 Neighboring gene transfer RNA threonine (anticodon GGU) Neighboring gene 40S ribosomal protein S24-like Neighboring gene 60S ribosomal protein L26-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046293.1 Chromosome 10 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
xylosyl- and glucuronyltransferase LARGE1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046293.1 Reference mRhiFer1_v1.p

    Range
    11985978..12480371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033117375.1 → XP_032973266.1  xylosyl- and glucuronyltransferase LARGE1 isoform X2

    UniProtKB/TrEMBL
    A0A671EIE9
    Conserved Domains (2) summary
    cd06431
    Location:138 → 417
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:473 → 734
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  2. XM_033117374.1 → XP_032973265.1  xylosyl- and glucuronyltransferase LARGE1 isoform X1

    UniProtKB/TrEMBL
    A0A671EEM7, A0A671EIE9
    Related
    ENSRFEP00010010183.1, ENSRFET00010011138.2
    Conserved Domains (2) summary
    cd06431
    Location:138 → 417
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:473 → 742
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  3. XM_033117376.1 → XP_032973267.1  xylosyl- and glucuronyltransferase LARGE1 isoform X3

    UniProtKB/TrEMBL
    A0A671EAL9
    Related
    ENSRFEP00010034716.1, ENSRFET00010060652.1
    Conserved Domains (2) summary
    cd06431
    Location:35 → 314
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:370 → 639
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
Nucleotide Protein
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