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DGKA diacylglycerol kinase alpha [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117028396, updated on 18-Sep-2024

Summary

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Gene symbol
DGKA
Gene description
diacylglycerol kinase alpha
See related
EnsemblRapid:ENSRFEG00010007329
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See DGKA in Genome Data Viewer
Location:
chromosome: 10
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 10 NC_046293.1 (55342198..55361103)

Chromosome 10 - NC_046293.1Genomic Context describing neighboring genes Neighboring gene matrix metallopeptidase 19 Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene premelanosome protein Neighboring gene cyclin dependent kinase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046293.1 Chromosome 10 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046293.1 Reference mRhiFer1_v1.p

    Range
    55342198..55361103
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033116898.1 → XP_032972789.1  diacylglycerol kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A7J7WPB3, A0A7J7WPM3
    Related
    ENSRFEP00010040890.1, ENSRFET00010053089.1
    Conserved Domains (6) summary
    smart00045
    Location:518 → 699
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:376 → 497
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20799
    Location:200 → 260
    C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
    cd20890
    Location:269 → 330
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

  2. XM_033116897.1 → XP_032972788.1  diacylglycerol kinase alpha isoform X2

    UniProtKB/TrEMBL
    A0A7J7WPB3, A0A7J7WPM3
    Related
    ENSRFEP00010010861.2, ENSRFET00010011873.2
    Conserved Domains (6) summary
    smart00045
    Location:518 → 699
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:376 → 497
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:113 → 182
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:4 → 109
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20799
    Location:200 → 260
    C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
    cd20890
    Location:269 → 330
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

  3. XM_033116896.1 → XP_032972787.1  diacylglycerol kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A7J7WPB3
    Related
    ENSRFEP00010036341.1, ENSRFET00010049490.1
    Conserved Domains (6) summary
    smart00045
    Location:558 → 739
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:416 → 537
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:44 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20799
    Location:240 → 300
    C1_DGK_typeI_rpt1; first protein kinase C conserved region 1 (C1 domain) found in type I diacylglycerol kinases
    cd20890
    Location:309 → 370
    C1_DGKalpha_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase alpha (DAG kinase alpha) and similar proteins

RNA

  1. XR_004424118.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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