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RBPJ recombination signal binding protein for immunoglobulin kappa J region [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117022159, updated on 30-Mar-2024

Summary

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Gene symbol
RBPJ
Gene description
recombination signal binding protein for immunoglobulin kappa J region
See related
EnsemblRapid:ENSRFEG00010000987
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See RBPJ in Genome Data Viewer
Location:
chromosome: 5
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 5 NC_046288.1 (70371457..70572284, complement)

Chromosome 5 - NC_046288.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 19 Neighboring gene pantothenate kinase 3-like Neighboring gene cholecystokinin A receptor Neighboring gene uncharacterized LOC117022160 Neighboring gene small integral membrane protein 20

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046288.1 Chromosome 5 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MAML1-RBP-Jkappa- ICN1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
recombining binding protein suppressor of hairless

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046288.1 Reference mRhiFer1_v1.p

    Range
    70371457..70572284 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033105911.1 → XP_032961802.1  recombining binding protein suppressor of hairless isoform X3

    UniProtKB/TrEMBL
    A0A140YWX1, A0A671DT49
    Related
    ENSRFEP00010041809.1, ENSRFET00010060294.1
    Conserved Domains (3) summary
    cd01176
    Location:336 → 432
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:192 → 314
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:34 → 159
    LAG1-DNAbind; LAG1, DNA binding

  2. XM_033105906.1 → XP_032961797.1  recombining binding protein suppressor of hairless isoform X1

    UniProtKB/TrEMBL
    A0A140YWX1
    Related
    ENSRFEP00010047317.1, ENSRFET00010061390.1
    Conserved Domains (3) summary
    cd01176
    Location:350 → 446
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:206 → 328
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:48 → 173
    LAG1-DNAbind; LAG1, DNA binding

  3. XM_033105910.1 → XP_032961801.1  recombining binding protein suppressor of hairless isoform X3

    UniProtKB/TrEMBL
    A0A140YWX1, A0A671DT49
    Conserved Domains (3) summary
    cd01176
    Location:336 → 432
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:192 → 314
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:34 → 159
    LAG1-DNAbind; LAG1, DNA binding

  4. XM_033105908.1 → XP_032961799.1  recombining binding protein suppressor of hairless isoform X2

    UniProtKB/TrEMBL
    A0A140YWX1, A0A671DK44
    Related
    ENSRFEP00010001391.1, ENSRFET00010001535.2
    Conserved Domains (3) summary
    cd01176
    Location:337 → 433
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:193 → 315
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:35 → 160
    LAG1-DNAbind; LAG1, DNA binding

  5. XM_033105909.1 → XP_032961800.1  recombining binding protein suppressor of hairless isoform X3

    UniProtKB/TrEMBL
    A0A140YWX1, A0A671DT49
    Related
    ENSRFEP00010001369.2, ENSRFET00010001510.2
    Conserved Domains (3) summary
    cd01176
    Location:336 → 432
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:192 → 314
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:34 → 159
    LAG1-DNAbind; LAG1, DNA binding

  6. XM_033105912.1 → XP_032961803.1  recombining binding protein suppressor of hairless isoform X4

    UniProtKB/TrEMBL
    A0A140YWX1
    Related
    ENSRFEP00010036366.1, ENSRFET00010047861.1
    Conserved Domains (3) summary
    cd01176
    Location:319 → 415
    IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...
    pfam09270
    Location:175 → 297
    BTD; Beta-trefoil DNA-binding domain
    pfam09271
    Location:17 → 142
    LAG1-DNAbind; LAG1, DNA binding
Nucleotide Protein
Heading Accession and Version

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