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ASAH1 N-acylsphingosine amidohydrolase 1 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117021668, updated on 30-Mar-2024

Summary

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Gene symbol
ASAH1
Gene description
N-acylsphingosine amidohydrolase 1
See related
EnsemblRapid:ENSRFEG00010011951
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See ASAH1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 4 NC_046287.1 (73140072..73173829, complement)

Chromosome 4 - NC_046287.1Genomic Context describing neighboring genes Neighboring gene fibrinogen like 1 Neighboring gene pericentriolar material 1 Neighboring gene heat shock cognate 71 kDa protein-like Neighboring gene FSHD region gene 1 Neighboring gene protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046287.1 Chromosome 4 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylsphingosine amidohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty acid amide hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
acid ceramidase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046287.1 Reference mRhiFer1_v1.p

    Range
    73140072..73173829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033104908.1 → XP_032960799.1  acid ceramidase

    UniProtKB/TrEMBL
    A0A671EX45, A0A671EXF7
    Related
    ENSRFEP00010017965.1, ENSRFET00010019586.2
    Conserved Domains (2) summary
    cd01903
    Location:134 → 379
    Ntn_AC_NAAA; AC_NAAA This conserved domain includes two closely related proteins, acid ceramidase (AC, also known as N-acylsphingosine amidohydrolase), and N-acylethanolamine-hydrolyzing acid amidase (NAAA). AC catalyzes the hydrolysis of ceramide to sphingosine and ...
    pfam15508
    Location:45 → 108
    NAAA-beta; beta subunit of N-acylethanolamine-hydrolyzing acid amidase
Nucleotide Protein
Heading Accession and Version

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