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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117019122, updated on 30-Mar-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
EnsemblRapid:ENSRFEG00010016244
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 5 Unlocalized Scaffold NW_022680355.1 (12145984..12214350)

NW_022680355.1Genomic Context describing neighboring genes Neighboring gene interleukin 15 receptor subunit alpha Neighboring gene interleukin 2 receptor subunit alpha Neighboring gene RNA binding motif protein 17 Neighboring gene inhibitor of growth protein 3-like Neighboring gene protein kinase C theta

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_022680355 Chromosome 5 Unlocalized Scaffold Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NW_022680355.1 Reference mRhiFer1_v1.p

    Range
    12145984..12214350
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033100529.1 → XP_032956420.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    UniProtKB/TrEMBL
    A0A671FFJ6
    Related
    ENSRFEP00010024377.2, ENSRFET00010026500.2
    Conserved Domains (2) summary
    pfam00300
    Location:229 → 412
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:4 → 226
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_033100530.1 → XP_032956421.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    UniProtKB/TrEMBL
    A0A671FG82, A0A7J7ZE92
    Related
    ENSRFEP00010044809.1, ENSRFET00010038240.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_033100532.1 → XP_032956423.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X5

    UniProtKB/TrEMBL
    A0A7J7ZDG6, A0A7J7ZE92
    Related
    ENSRFEP00010024595.2, ENSRFET00010026733.2
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_033100531.1 → XP_032956422.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

    UniProtKB/TrEMBL
    A0A671FLW0, A0A7J7ZE92
    Related
    ENSRFEP00010024664.1, ENSRFET00010026807.2
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_033100528.1 → XP_032956419.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    UniProtKB/TrEMBL
    A0A7J7ZE92
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_033100534.1 → XP_032956425.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X7

    UniProtKB/TrEMBL
    A0A7J7ZE92
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  7. XM_033100533.1 → XP_032956424.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X6

    UniProtKB/TrEMBL
    A0A7J7ZE92
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 432
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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