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PLCB4 phospholipase C beta 4 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117015942, updated on 30-Mar-2024

Summary

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Gene symbol
PLCB4
Gene description
phospholipase C beta 4
See related
EnsemblRapid:ENSRFEG00010019756
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See PLCB4 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 23 NC_046306.1 (29886640..30279644)

Chromosome 23 - NC_046306.1Genomic Context describing neighboring genes Neighboring gene thioredoxin related transmembrane protein 4 Neighboring gene phospholipase C beta 1 Neighboring gene U6 spliceosomal RNA Neighboring gene 40S ribosomal protein S26-like Neighboring gene lysosomal associated membrane protein family member 5 Neighboring gene p21 (RAC1) activated kinase 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046306.1 Chromosome 23 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046306.1 Reference mRhiFer1_v1.p

    Range
    29886640..30279644
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033094862.1 → XP_032950753.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A671FVR7, A0A671FVY2
    Related
    ENSRFEP00010029821.2, ENSRFET00010032357.2
    Conserved Domains (6) summary
    PTZ00121
    Location:859 → 1206
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  2. XM_033094858.1 → XP_032950749.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A671FVR7, A0A671FVY2
    Related
    ENSRFEP00010036081.1, ENSRFET00010045368.1
    Conserved Domains (6) summary
    PTZ00121
    Location:859 → 1206
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  3. XM_033094863.1 → XP_032950754.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A671FVY2, A0A671G538
    Related
    ENSRFEP00010029912.1, ENSRFET00010032452.2
    Conserved Domains (6) summary
    PTZ00121
    Location:851 → 1182
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  4. XM_033094861.1 → XP_032950752.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A671FVR7, A0A671FVY2
    Conserved Domains (6) summary
    PTZ00121
    Location:859 → 1206
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  5. XM_033094864.1 → XP_032950755.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X2

    UniProtKB/TrEMBL
    A0A671FVY2, A0A671G538
    Conserved Domains (6) summary
    PTZ00121
    Location:851 → 1182
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)

  6. XM_033094859.1 → XP_032950750.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1

    UniProtKB/TrEMBL
    A0A671FVR7, A0A671FVY2
    Conserved Domains (6) summary
    PTZ00121
    Location:859 → 1206
    PTZ00121; MAEBL; Provisional
    cd00275
    Location:714 → 830
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:312 → 680
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    cd13361
    Location:17 → 143
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    cd16211
    Location:148 → 300
    EFh_PI-PLCbeta4; EF-hand motif found in phosphoinositide phospholipase C beta 4 (PI-PLC-beta4)
    pfam06631
    Location:926 → 967
    DUF1154; Protein of unknown function (DUF1154)
Nucleotide Protein
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