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PTGS2 prostaglandin-endoperoxide synthase 2 [ Rhinolophus ferrumequinum (greater horseshoe bat) ]

Gene ID: 117014281, updated on 30-Mar-2024

Summary

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Gene symbol
PTGS2
Gene description
prostaglandin-endoperoxide synthase 2
See related
EnsemblRapid:ENSRFEG00010013243
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus ferrumequinum
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
Orthologs
human mouse all
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Genomic context

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See PTGS2 in Genome Data Viewer
Location:
chromosome: 22
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_02 current mRhiFer1_v1.p (GCF_004115265.2) 22 NC_046305.1 (17294919..17300218, complement)

Chromosome 22 - NC_046305.1Genomic Context describing neighboring genes Neighboring gene translocated promoter region, nuclear basket protein Neighboring gene odr-4 GPCR localization factor homolog Neighboring gene phosducin Neighboring gene phospholipase A2 group IVA Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046305.1 Chromosome 22 Reference mRhiFer1_v1.p

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peroxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables prostaglandin-endoperoxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cyclooxygenase pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin G/H synthase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_004115265.2-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRhiFer1_v1.p

Genomic

  1. NC_046305.1 Reference mRhiFer1_v1.p

    Range
    17294919..17300218 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_033091977.1 → XP_032947868.1  prostaglandin G/H synthase 2

    UniProtKB/TrEMBL
    A0A671FBA3
    Related
    ENSRFEP00010019707.1, ENSRFET00010021450.2
    Conserved Domains (2) summary
    cd09816
    Location:76 → 563
    prostaglandin_endoperoxide_synthase; Animal prostaglandin endoperoxide synthase and related bacterial proteins
    cd00054
    Location:20 → 56
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
Nucleotide Protein
Heading Accession and Version

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