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LOC116957458 TNF receptor-associated factor 2-like [ Petromyzon marinus (sea lamprey) ]

Gene ID: 116957458, updated on 1-Aug-2024

Summary

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Gene symbol
LOC116957458
Gene description
TNF receptor-associated factor 2-like
See related
EnsemblRapid:ENSPMAG00000032987
Gene type
protein coding
RefSeq status
MODEL
Organism
Petromyzon marinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata; Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon
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Genomic context

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Location:
chromosome: 74
Exon count:
14
Annotation release Status Assembly Chr Location
100 current kPetMar1.pri (GCF_010993605.1) 74 NC_046142.1 (1951464..1984427, complement)

Chromosome 74 - NC_046142.1Genomic Context describing neighboring genes Neighboring gene L-selectin-like Neighboring gene L-selectin-like Neighboring gene uncharacterized LOC116957454 Neighboring gene rab GTPase-activating protein 1-like Neighboring gene surfeit 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_046142.1 Chromosome 74 Reference kPetMar1.pri Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Petromyzon marinus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference kPetMar1.pri Primary Assembly

Genomic

  1. NC_046142.1 Reference kPetMar1.pri Primary Assembly

    Range
    1951464..1984427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032979616.1 → XP_032835507.1  TNF receptor-associated factor 2-like isoform X4

    UniProtKB/TrEMBL
    A0AAJ7XIL3
    Related
    ENSPMAP00000047172.1, ENSPMAT00000065883.1
    Conserved Domains (5) summary
    PLN03086
    Location:184 → 257
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:443 → 630
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:398 → 458
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:80 → 106
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:227 → 284
    zf-TRAF; TRAF-type zinc finger

  2. XM_032979613.1 → XP_032835504.1  TNF receptor-associated factor 2-like isoform X2

    UniProtKB/TrEMBL
    A0AAJ7UIS4
    Conserved Domains (5) summary
    PLN03086
    Location:188 → 261
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:447 → 634
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:402 → 462
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:84 → 110
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:231 → 288
    zf-TRAF; TRAF-type zinc finger

  3. XM_032979617.1 → XP_032835508.1  TNF receptor-associated factor 2-like isoform X5

    UniProtKB/TrEMBL
    A0AAJ7UFU0
    Conserved Domains (5) summary
    PLN03086
    Location:132 → 205
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:391 → 578
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:346 → 406
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:28 → 54
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:175 → 232
    zf-TRAF; TRAF-type zinc finger

  4. XM_032979612.1 → XP_032835503.1  TNF receptor-associated factor 2-like isoform X2

    UniProtKB/TrEMBL
    A0AAJ7UIS4
    Related
    ENSPMAP00000029684.1, ENSPMAT00000059697.1
    Conserved Domains (5) summary
    PLN03086
    Location:188 → 261
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:447 → 634
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:402 → 462
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:84 → 110
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:231 → 288
    zf-TRAF; TRAF-type zinc finger

  5. XM_032979618.1 → XP_032835509.1  TNF receptor-associated factor 2-like isoform X5

    UniProtKB/TrEMBL
    A0AAJ7UFU0
    Conserved Domains (5) summary
    PLN03086
    Location:132 → 205
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:391 → 578
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:346 → 406
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:28 → 54
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:175 → 232
    zf-TRAF; TRAF-type zinc finger

  6. XM_032979614.1 → XP_032835505.1  TNF receptor-associated factor 2-like isoform X2

    UniProtKB/TrEMBL
    A0AAJ7UIS4
    Conserved Domains (5) summary
    PLN03086
    Location:188 → 261
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:447 → 634
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:402 → 462
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:84 → 110
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:231 → 288
    zf-TRAF; TRAF-type zinc finger

  7. XM_032979615.1 → XP_032835506.1  TNF receptor-associated factor 2-like isoform X3

    UniProtKB/TrEMBL
    A0AAJ7XIB5
    Conserved Domains (5) summary
    COG5236
    Location:139 → 201
    COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    cl02446
    Location:447 → 634
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:402 → 462
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:137 → 163
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:231 → 288
    zf-TRAF; TRAF-type zinc finger

  8. XM_032979611.1 → XP_032835502.1  TNF receptor-associated factor 2-like isoform X1

    UniProtKB/TrEMBL
    A0AAJ7UIM5
    Related
    ENSPMAP00000029292.1, ENSPMAT00000028799.1
    Conserved Domains (5) summary
    PLN03086
    Location:241 → 314
    PLN03086; PRLI-interacting factor K; Provisional
    cl02446
    Location:500 → 687
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    pfam16673
    Location:455 → 515
    TRAF_BIRC3_bd; TNF receptor-associated factor BIRC3 binding domain
    cl17238
    Location:137 → 163
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:284 → 341
    zf-TRAF; TRAF-type zinc finger
Nucleotide Protein
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