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TDP2 tyrosyl-DNA phosphodiesterase 2 [ Lontra canadensis (Northern American river otter) ]

Gene ID: 116869986, updated on 18-Mar-2024

Summary

Gene symbol
TDP2
Gene description
tyrosyl-DNA phosphodiesterase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Lontra canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Lutrinae; Lontra
Orthologs
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Genomic context

See TDP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
100 current GSC_riverotter_1.0 (GCF_010015895.1) Unplaced Scaffold NW_022631015.1 (22427638..22442198, complement)

NW_022631015.1Genomic Context describing neighboring genes Neighboring gene KIAA0319 ortholog Neighboring gene U6 spliceosomal RNA Neighboring gene acyl-CoA thioesterase 13 Neighboring gene chromosome unknown C6orf62 homolog

Genomic regions, transcripts, and products

Genomic Sequence:
NW_022631015 Unplaced Scaffold Reference GSC_riverotter_1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tyrosyl-DNA phosphodiesterase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lontra canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GSC_riverotter_1.0

Genomic

  1. NW_022631015.1 Reference GSC_riverotter_1.0

    Range
    22427638..22442198 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032861647.1XP_032717538.1  tyrosyl-DNA phosphodiesterase 2 isoform X2

    Conserved Domains (2) summary
    cd09080
    Location:110297
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:2359
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
  2. XM_032861646.1XP_032717537.1  tyrosyl-DNA phosphodiesterase 2 isoform X1

    Conserved Domains (2) summary
    cd09080
    Location:110354
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:2359
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
  3. XM_032861645.1XP_032717536.1  tyrosyl-DNA phosphodiesterase 2 isoform X1

    Conserved Domains (2) summary
    cd09080
    Location:110354
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:2359
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins