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PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial [ Chelonoidis abingdonii (Abingdon island giant tortoise) ]

Gene ID: 116839052, updated on 18-Mar-2024

Summary

Gene symbol
PCK2
Gene description
phosphoenolpyruvate carboxykinase 2, mitochondrial
See related
Ensembl:ENSCABG00000005055
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonoidis abingdonii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Testudinidae; Chelonoidis
Orthologs
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Genomic context

See PCK2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current ASM359739v1 (GCF_003597395.1) Unplaced Scaffold NW_022646253.1 (13565..19714)

NW_022646253.1Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 11 Neighboring gene proteasome activator complex subunit 1-like

Genomic regions, transcripts, and products

Genomic Sequence:
NW_022646253 Unplaced Scaffold Reference ASM359739v1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase [GTP], mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonoidis abingdonii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM359739v1

Genomic

  1. NW_022646253.1 Reference ASM359739v1

    Range
    13565..19714
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032804705.1XP_032660596.1  phosphoenolpyruvate carboxykinase [GTP], mitochondrial

    UniProtKB/TrEMBL
    A0A8C0GEY0, A0A8C0GMG4
    Related
    ENSCABP00000006706.1, ENSCABT00000007332.1
    Conserved Domains (1) summary
    cd00819
    Location:1499
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...