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TJP2 tight junction protein 2 [ Phocoena sinus (vaquita) ]

Gene ID: 116755638, updated on 18-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
Ensembl:ENSPSNG00000014370
Gene type
protein coding
RefSeq status
MODEL
Organism
Phocoena sinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Phocoenidae; Phocoena
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
25
Annotation release Status Assembly Chr Location
100 current mPhoSin1.pri (GCF_008692025.1) 6 NC_045768.1 (50574476..50712539, complement)

Chromosome 6 - NC_045768.1Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene hypoxanthine-guanine phosphoribosyltransferase-like Neighboring gene UDP-N-acetylglucosamine transporter-like Neighboring gene uncharacterized LOC116755643 Neighboring gene frataxin Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045768.1 Chromosome 6 Reference mPhoSin1.pri

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phocoena sinus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mPhoSin1.pri

Genomic

  1. NC_045768.1 Reference mPhoSin1.pri

    Range
    50574476..50712539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032635390.1 → XP_032491281.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A8C9C812, A0A8C9CCV7
    Related
    ENSPSNP00000020818.1, ENSPSNT00000023451.1
    Conserved Domains (5) summary
    cd12027
    Location:574 → 636
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:670 → 849
    GuKc; Guanylate kinase homologues
    smart00228
    Location:278 → 355
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 266
    RSRP; Arginine/Serine-Rich protein 1

  2. XM_032635388.1 → XP_032491279.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C9C812, A0A8C9E5G7
    Related
    ENSPSNP00000020897.1, ENSPSNT00000023534.1
    Conserved Domains (5) summary
    cd12027
    Location:574 → 636
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:670 → 849
    GuKc; Guanylate kinase homologues
    smart00228
    Location:278 → 355
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:125 → 266
    RSRP; Arginine/Serine-Rich protein 1

  3. XM_032635389.1 → XP_032491280.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C9C812
    Related
    ENSPSNP00000021014.1, ENSPSNT00000023662.1
    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:301 → 378
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:148 → 289
    RSRP; Arginine/Serine-Rich protein 1

  4. XM_032635387.1 → XP_032491278.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C9C812, A0A8C9E5K3
    Related
    ENSPSNP00000021089.1, ENSPSNT00000023744.1
    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:301 → 378
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam17069
    Location:148 → 289
    RSRP; Arginine/Serine-Rich protein 1
Nucleotide Protein
Heading Accession and Version

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