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plcg1 phospholipase C, gamma 1 [ Etheostoma spectabile (orangethroat darter) ]

Gene ID: 116692557, updated on 18-Mar-2024

Summary

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Gene symbol
plcg1
Gene description
phospholipase C, gamma 1
Locus tag
FQN60_001907
Gene type
protein coding
RefSeq status
MODEL
Organism
Etheostoma spectabile
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Etheostomatinae; Etheostoma
Orthologs
human zebrafish all
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Genomic context

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See plcg1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
33
Annotation release Status Assembly Chr Location
100 current UIUC_Espe_1.0 (GCF_008692095.1) 7 NC_045739.1 (7612972..7640624, complement)

Chromosome 7 - NC_045739.1Genomic Context describing neighboring genes Neighboring gene RAB5 interacting factor Neighboring gene zinc fingers and homeoboxes 3b Neighboring gene DNA topoisomerase Ib Neighboring gene nuclear receptor coactivator 6

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045739.1 Chromosome 7 Reference UIUC_Espe_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Etheostoma spectabile Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UIUC_Espe_1.0 Primary Assembly

Genomic

  1. NC_045739.1 Reference UIUC_Espe_1.0 Primary Assembly

    Range
    7612972..7640624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032520943.1 → XP_032376834.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2

    UniProtKB/TrEMBL
    A0A5J5DBI0
    Conserved Domains (9) summary
    smart00149
    Location:950 → 1065
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1084 → 1207
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:314 → 492
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:658 → 760
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:540 → 644
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:786 → 845
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cl28895
    Location:156 → 301
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl17171
    Location:855 → 929
    PH-like; Pleckstrin homology-like domain

  2. XM_032520945.1 → XP_032376836.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X3

    UniProtKB/TrEMBL
    A0A5J5DBI0
    Conserved Domains (9) summary
    smart00149
    Location:951 → 1066
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1085 → 1208
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:314 → 492
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:658 → 760
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:540 → 644
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:786 → 845
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cl28895
    Location:156 → 301
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl17171
    Location:856 → 930
    PH-like; Pleckstrin homology-like domain

  3. XM_032520942.1 → XP_032376833.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

    UniProtKB/TrEMBL
    A0A5J5DBI0
    Conserved Domains (9) summary
    smart00149
    Location:951 → 1066
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1085 → 1208
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:314 → 492
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:658 → 760
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:540 → 644
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:786 → 845
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cl28895
    Location:156 → 301
    EFh_PI-PLC; EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes
    cl17171
    Location:856 → 930
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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