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LOC116689879 tight junction protein ZO-2-like [ Etheostoma spectabile (orangethroat darter) ]

Gene ID: 116689879, updated on 18-Mar-2024

Summary

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Gene symbol
LOC116689879
Gene description
tight junction protein ZO-2-like
Gene type
protein coding
RefSeq status
MODEL
Organism
Etheostoma spectabile
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Etheostomatinae; Etheostoma
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Genomic context

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See LOC116689879 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
26
Annotation release Status Assembly Chr Location
100 current UIUC_Espe_1.0 (GCF_008692095.1) 5 NC_045737.1 (31174946..31246646)

Chromosome 5 - NC_045737.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxy-3-methylglutaryl-coenzyme A reductase-like Neighboring gene frataxin Neighboring gene 5S ribosomal RNA Neighboring gene 5S ribosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045737.1 Chromosome 5 Reference UIUC_Espe_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Etheostoma spectabile Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UIUC_Espe_1.0 Primary Assembly

Genomic

  1. NC_045737.1 Reference UIUC_Espe_1.0 Primary Assembly

    Range
    31174946..31246646
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032516531.1 → XP_032372422.1  tight junction protein ZO-2-like isoform X1

    Conserved Domains (5) summary
    smart00072
    Location:627 → 805
    GuKc; Guanylate kinase homologues
    smart00228
    Location:235 → 315
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    PHA03247
    Location:1016 → 1180
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:434 → 511
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:528 → 593
    SH3; Src Homology 3 domain superfamily

  2. XM_032516534.1 → XP_032372425.1  tight junction protein ZO-2-like isoform X2

    Conserved Domains (4) summary
    smart00072
    Location:627 → 805
    GuKc; Guanylate kinase homologues
    smart00228
    Location:235 → 315
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:434 → 511
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:528 → 593
    SH3; Src Homology 3 domain superfamily

  3. XM_032516535.1 → XP_032372426.1  tight junction protein ZO-2-like isoform X3

    Conserved Domains (4) summary
    smart00072
    Location:627 → 805
    GuKc; Guanylate kinase homologues
    smart00228
    Location:235 → 315
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:434 → 511
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:528 → 593
    SH3; Src Homology 3 domain superfamily

  4. XM_032516532.1 → XP_032372423.1  tight junction protein ZO-2-like isoform X1

    Conserved Domains (5) summary
    smart00072
    Location:627 → 805
    GuKc; Guanylate kinase homologues
    smart00228
    Location:235 → 315
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    PHA03247
    Location:1016 → 1180
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:434 → 511
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:528 → 593
    SH3; Src Homology 3 domain superfamily

  5. XM_032516533.1 → XP_032372424.1  tight junction protein ZO-2-like isoform X1

    Conserved Domains (5) summary
    smart00072
    Location:627 → 805
    GuKc; Guanylate kinase homologues
    smart00228
    Location:235 → 315
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    PHA03247
    Location:1016 → 1180
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:434 → 511
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cl17036
    Location:528 → 593
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
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