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pikfyve phosphoinositide kinase, FYVE finger containing [ Etheostoma spectabile (orangethroat darter) ]

Gene ID: 116688950, updated on 18-Mar-2024

Summary

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Gene symbol
pikfyve
Gene description
phosphoinositide kinase, FYVE finger containing
Locus tag
FQN60_018539
Gene type
protein coding
RefSeq status
MODEL
Organism
Etheostoma spectabile
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Percoidei; Percidae; Etheostomatinae; Etheostoma
Orthologs
human zebrafish all
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Genomic context

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See pikfyve in Genome Data Viewer
Location:
chromosome: 5
Exon count:
42
Annotation release Status Assembly Chr Location
100 current UIUC_Espe_1.0 (GCF_008692095.1) 5 NC_045737.1 (35803841..35845553)

Chromosome 5 - NC_045737.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116688949 Neighboring gene chromosome 5 C2orf80 homolog Neighboring gene uncharacterized LOC116688948 Neighboring gene ankyrin repeat domain 44 Neighboring gene splicing factor 3b, subunit 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045737.1 Chromosome 5 Reference UIUC_Espe_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: 1-phosphatidylinositol 3-phosphate 5-kinase
Names
phosphoinositide kinase, FYVE-type zinc finger containing

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Etheostoma spectabile Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UIUC_Espe_1.0 Primary Assembly

Genomic

  1. NC_045737.1 Reference UIUC_Espe_1.0 Primary Assembly

    Range
    35803841..35845553
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032515167.1 → XP_032371058.1  LOW QUALITY PROTEIN: 1-phosphatidylinositol 3-phosphate 5-kinase

    Conserved Domains (4) summary
    cd03334
    Location:652 → 912
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:392 → 473
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:184 → 245
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins
    cd17300
    Location:1831 → 2097
    PIPKc_PIKfyve; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in 1-phosphatidylinositol-3-phosphate 5-kinase and similar proteins
Nucleotide Protein
Heading Accession and Version

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