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IGF1R insulin like growth factor 1 receptor [ Aythya fuligula (tufted duck) ]

Gene ID: 116493472, updated on 25-Jun-2024

Summary

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Gene symbol
IGF1R
Gene description
insulin like growth factor 1 receptor
See related
EnsemblRapid:ENSAFUG00000000725
Gene type
protein coding
RefSeq status
MODEL
Organism
Aythya fuligula
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Aythyinae; Aythya
Orthologs
human mouse all
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Genomic context

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See IGF1R in Genome Data Viewer
Location:
chromosome: 11
Exon count:
21
Annotation release Status Assembly Chr Location
100 current bAytFul2.pri (GCF_009819795.1) 11 NC_045569.1 (17733744..17902715, complement)

Chromosome 11 - NC_045569.1Genomic Context describing neighboring genes Neighboring gene arrestin domain containing 4 Neighboring gene Protein FAM169B Neighboring gene pyroglutamyl-peptidase I like Neighboring gene synemin Neighboring gene leucine rich repeat containing 28

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045569.1 Chromosome 11 Reference bAytFul2.pri Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor substrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of insulin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-like growth factor 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Aythya fuligula Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bAytFul2.pri Primary Assembly

Genomic

  1. NC_045569.1 Reference bAytFul2.pri Primary Assembly

    Range
    17733744..17902715 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032194908.1 → XP_032050799.1  insulin-like growth factor 1 receptor isoform X2

    UniProtKB/TrEMBL
    A0A6J3DJS0
    Conserved Domains (4) summary
    cd00063
    Location:835 → 924
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:175 → 330
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:351 → 464
    Recep_L_domain; Receptor L domain
    cl21453
    Location:992 → 1279
    PKc_like; Protein Kinases, catalytic domain

  2. XM_032194907.1 → XP_032050798.1  insulin-like growth factor 1 receptor isoform X1

    UniProtKB/TrEMBL
    A0A6J3DN84
    Related
    ENSAFUP00000001049.1, ENSAFUT00000001107.1
    Conserved Domains (4) summary
    cd00063
    Location:835 → 924
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:175 → 330
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:351 → 464
    Recep_L_domain; Receptor L domain
    cl21453
    Location:993 → 1280
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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