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PAK6 p21 (RAC1) activated kinase 6 [ Aythya fuligula (tufted duck) ]

Gene ID: 116490056, updated on 25-Jun-2024

Summary

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Gene symbol
PAK6
Gene description
p21 (RAC1) activated kinase 6
See related
EnsemblRapid:ENSAFUG00000014378
Gene type
protein coding
RefSeq status
MODEL
Organism
Aythya fuligula
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Aythyinae; Aythya
Orthologs
human mouse all
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Genomic context

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See PAK6 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
16
Annotation release Status Assembly Chr Location
100 current bAytFul2.pri (GCF_009819795.1) 5 NC_045563.1 (19094842..19136072, complement)

Chromosome 5 - NC_045563.1Genomic Context describing neighboring genes Neighboring gene InaF motif containing 2 Neighboring gene phospholipase C beta 2 Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene cadherin related family member 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045563.1 Chromosome 5 Reference bAytFul2.pri Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Aythya fuligula Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bAytFul2.pri Primary Assembly

Genomic

  1. NC_045563.1 Reference bAytFul2.pri Primary Assembly

    Range
    19094842..19136072 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032188921.1 → XP_032044812.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A6J3D5H3
    Conserved Domains (2) summary
    cd01093
    Location:41 → 86
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:402 → 698
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  2. XM_032188925.1 → XP_032044816.1  serine/threonine-protein kinase PAK 6 isoform X3

    UniProtKB/TrEMBL
    A0A6J3D2Y9
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  3. XM_032188920.1 → XP_032044811.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A6J3D5H3
    Conserved Domains (2) summary
    cd01093
    Location:41 → 86
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:402 → 698
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  4. XM_032188922.1 → XP_032044813.1  serine/threonine-protein kinase PAK 6 isoform X1

    UniProtKB/TrEMBL
    A0A6J3D5H3
    Related
    ENSAFUP00000019225.1, ENSAFUT00000024203.1
    Conserved Domains (2) summary
    cd01093
    Location:41 → 86
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:402 → 698
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  5. XM_032188924.1 → XP_032044815.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A6J3D2Y4
    Conserved Domains (2) summary
    cd01093
    Location:36 → 81
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:397 → 693
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  6. XM_032188930.1 → XP_032044821.1  serine/threonine-protein kinase PAK 6 isoform X3

    UniProtKB/TrEMBL
    A0A6J3D2Y9
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  7. XM_032188923.1 → XP_032044814.1  serine/threonine-protein kinase PAK 6 isoform X2

    UniProtKB/TrEMBL
    A0A6J3D2Y4
    Related
    ENSAFUP00000019222.1, ENSAFUT00000024196.1
    Conserved Domains (2) summary
    cd01093
    Location:36 → 81
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:397 → 693
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  8. XM_032188926.1 → XP_032044817.1  serine/threonine-protein kinase PAK 6 isoform X3

    UniProtKB/TrEMBL
    A0A6J3D2Y9
    Related
    ENSAFUP00000019218.1, ENSAFUT00000024187.1
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  9. XM_032188927.1 → XP_032044818.1  serine/threonine-protein kinase PAK 6 isoform X3

    UniProtKB/TrEMBL
    A0A6J3D2Y9
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  10. XM_032188928.1 → XP_032044819.1  serine/threonine-protein kinase PAK 6 isoform X3

    UniProtKB/TrEMBL
    A0A6J3D2Y9
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:371 → 667
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
Nucleotide Protein
Heading Accession and Version

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