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PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 [ Hylobates moloch (silvery gibbon) ]

Gene ID: 116467288, updated on 18-Mar-2024

Summary

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Gene symbol
PFKFB3
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
See related
EnsemblRapid:ENSHMOG00010000234
Gene type
protein coding
RefSeq status
MODEL
Organism
Hylobates moloch
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Hylobates
Orthologs
human mouse all
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Genomic context

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See PFKFB3 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_07 current HMol_V3 (GCF_009828535.3) Unplaced Scaffold NW_026652277.1 (5904359..5998478)
100 previous assembly HMol (GCF_009828535.1) Unplaced Scaffold NW_022454843.1 (5904276..6017314)

NW_026652277.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA14 Neighboring gene interleukin 2 receptor subunit alpha Neighboring gene RNA binding motif protein 17 Neighboring gene syntenin-1-like Neighboring gene uncharacterized LOC116467662 Neighboring gene protein kinase C theta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009828535.3-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HMol_V3

Genomic

  1. NW_026652277.1 Reference HMol_V3

    Range
    5904359..5998478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032151194.2 → XP_032007085.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X4

    Conserved Domains (2) summary
    pfam00300
    Location:229 → 415
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:4 → 226
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_032151036.2 → XP_032006927.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2

    Related
    ENSHMOP00010000314.1, ENSHMOT00010000382.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_032150947.2 → XP_032006838.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X1

    Related
    ENSHMOP00010000308.1, ENSHMOT00010000376.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_032151116.2 → XP_032007007.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X3

    Related
    ENSHMOP00010000311.1, ENSHMOT00010000379.1
    Conserved Domains (2) summary
    pfam00300
    Location:249 → 435
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:26 → 246
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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