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HELZ2 helicase with zinc finger 2 [ Hylobates moloch (silvery gibbon) ]

Gene ID: 116460800, updated on 18-Mar-2024

Summary

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Gene symbol
HELZ2
Gene description
helicase with zinc finger 2
See related
EnsemblRapid:ENSHMOG00010015598
Gene type
protein coding
RefSeq status
MODEL
Organism
Hylobates moloch
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Hylobates
Orthologs
human mouse all
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Genomic context

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See HELZ2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_07 current HMol_V3 (GCF_009828535.3) Unplaced Scaffold NW_026652296.1 (696528..711249)
100 previous assembly HMol (GCF_009828535.1) Unplaced Scaffold NW_022454865.1 (696528..711255)

NW_026652296.1Genomic Context describing neighboring genes Neighboring gene stathmin 3 Neighboring gene glucocorticoid modulatory element binding protein 2 Neighboring gene fibronectin type III domain containing 11 Neighboring gene src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA nuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
helicase with zinc finger domain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009828535.3-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HMol_V3

Genomic

  1. NW_026652296.1 Reference HMol_V3

    Range
    696528..711249
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032141981.2 → XP_031997872.1  helicase with zinc finger domain 2 isoform X2

    Conserved Domains (4) summary
    smart00955
    Location:1334 → 1693
    RNB; This domain is the catalytic domain of ribonuclease II
    cd18040
    Location:2152 → 2434
    DEXXc_HELZ2-C; C-terminal DEXX-box helicase domain of HELZ2
    cd18076
    Location:514 → 744
    DEXXQc_HELZ2-N; N-terminal DEXXQ-box helicase domain of HELZ2
    pfam13087
    Location:2414 → 2619
    AAA_12; AAA domain

  2. XM_032141982.2 → XP_031997873.1  helicase with zinc finger domain 2 isoform X3

    Related
    ENSHMOP00010018631.1, ENSHMOT00010023636.1
    Conserved Domains (4) summary
    smart00955
    Location:1334 → 1693
    RNB; This domain is the catalytic domain of ribonuclease II
    cd18040
    Location:2152 → 2426
    DEXXc_HELZ2-C; C-terminal DEXX-box helicase domain of HELZ2
    cd18076
    Location:514 → 744
    DEXXQc_HELZ2-N; N-terminal DEXXQ-box helicase domain of HELZ2
    pfam13087
    Location:2406 → 2611
    AAA_12; AAA domain

  3. XM_032141980.1 → XP_031997871.1  helicase with zinc finger domain 2 isoform X1

    Conserved Domains (4) summary
    smart00955
    Location:1334 → 1693
    RNB; This domain is the catalytic domain of ribonuclease II
    cd18040
    Location:2152 → 2434
    DEXXc_HELZ2-C; C-terminal DEXX-box helicase domain of HELZ2
    cd18076
    Location:514 → 744
    DEXXQc_HELZ2-N; N-terminal DEXXQ-box helicase domain of HELZ2
    pfam13087
    Location:2414 → 2620
    AAA_12; AAA domain

  4. XM_058433022.1 → XP_058289005.1  helicase with zinc finger domain 2 isoform X4

  5. XM_032141983.1 → XP_031997874.1  helicase with zinc finger domain 2 isoform X5

    Conserved Domains (4) summary
    smart00955
    Location:1334 → 1693
    RNB; This domain is the catalytic domain of ribonuclease II
    cd18040
    Location:2152 → 2434
    DEXXc_HELZ2-C; C-terminal DEXX-box helicase domain of HELZ2
    cd18076
    Location:514 → 744
    DEXXQc_HELZ2-N; N-terminal DEXXQ-box helicase domain of HELZ2
    pfam13087
    Location:715 → 915
    AAA_12; AAA domain

  6. XM_058433023.1 → XP_058289006.1  helicase with zinc finger domain 2 isoform X5

RNA

  1. XR_004245911.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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