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EGILA EGFR interacting lncRNA [ Homo sapiens (human) ]

Gene ID: 116435281, updated on 10-Oct-2023

Summary

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Official Symbol
EGILAprovided by HGNC
Official Full Name
EGFR interacting lncRNAprovided by HGNC
Primary source
HGNC:HGNC:54482
See related
Ensembl:ENSG00000258451
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Lnc-EGFR
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Genomic context

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Location:
14q11.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (20693480..20706941, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (14890589..14904051, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (21161639..21175100, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8091 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8092 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5573 Neighboring gene tRNA-Tyr (anticodon GTA) 5-5 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5574 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8093 Neighboring gene tRNA-Pro (anticodon TGG) 3-2 Neighboring gene ribonuclease A family member 4 Neighboring gene angiogenin Neighboring gene ReSE screen-validated silencer GRCh37_chr14:21167810-21167975 Neighboring gene uncharacterized LOC124903282 Neighboring gene RAN binding protein 20 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion. Jiang R, et al. Nat Commun, 2017 May 25. PMID 28541302, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long noncoding-EGFR stimulates T-regulatory cell differentiation, suppresses cytotoxic T lymphocyte activity and promotes hepatocellular carcinoma growth in an EGFR-dependent manner.
    Title: The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See Variation Viewer (GRCh37.p13)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_174964.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL163636
    Related
    ENST00000554286.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    20693480..20706941 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    14890589..14904051 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases